Reactome | p-VAV family:PIP3:RAC1:GTP [plasma membrane]

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p-VAV family:PIP3:RAC1:GTP [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5357447] 2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] - Homo sapiens [Complex:R-HSA-5357447] 2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5357483] RAC1 binds PAK1-3 - Homo sapiens [Reaction:R-HSA-5357483] RAC1 binds PAK1-3 - Homo sapiens
created	[InstanceEdit:5218797] Garapati, P V, 2013-12-19
dbId	5218784
displayName	p-VAV family:PIP3:RAC1:GTP [plasma membrane]
hasComponent	[Complex:R-HSA-5218789] p-VAV family:PIP3 [plasma membrane] [Complex:R-HSA-442641] RAC1:GTP [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - Mus musculus [Complex:R-RNO-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - Rattus norvegicus [Complex:R-CFA-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - Canis familiaris [Complex:R-SSC-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - Sus scrofa [Complex:R-GGA-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - Gallus gallus [Complex:R-DME-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - Caenorhabditis elegans
isChimeric	false
maxDepth	4
modified	[InstanceEdit:9020713] Rothfels, Karen, 2017-09-11
name	p-VAV family:PIP3:RAC1:GTP
producedByEvent	[Reaction:R-HSA-5218850] VAV exchanges GTP for GDP on RAC1, activating it - Homo sapiens [Reaction:R-HSA-5357472] PAK1-3 autophosphorylates - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5218784
updateTrackers	[UpdateTracker:9898143] Update Tracker - [Complex:5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - v63:[add_removeHasComponent] [UpdateTracker:9896668] Update Tracker - [Complex:5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - v60:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9898143] Update Tracker - [Complex:5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - v63:[add_removeHasComponent] [UpdateTracker:9896668] Update Tracker - [Complex:5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - v60:[updateContainedComponent]
(input)	[Reaction:R-HSA-5357483] RAC1 binds PAK1-3
(hasComponent)	[Complex:R-HSA-5357447] 2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] [Complex:R-HSA-5357487] p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane]
(output)	[Reaction:R-HSA-5357472] PAK1-3 autophosphorylates [Reaction:R-HSA-5218850] VAV exchanges GTP for GDP on RAC1, activating it

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