Reactome | p-VAV family:PIP3:RAC1:GTP [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CEL-5357447] 2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] - Caenorhabditis elegans [Complex:R-CEL-5357447] 2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] - Caenorhabditis elegans
consumedByEvent	[Reaction:R-CEL-5357483] RAC1 binds PAK1-3 - Caenorhabditis elegans [Reaction:R-CEL-5357483] RAC1 binds PAK1-3 - Caenorhabditis elegans
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10964068
displayName	p-VAV family:PIP3:RAC1:GTP [plasma membrane]
hasComponent	[Complex:R-CEL-5218789] p-VAV family:PIP3 [plasma membrane] [Complex:R-CEL-442641] RAC1:GTP [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane] - Homo sapiens
maxDepth	3
name	p-VAV family:PIP3:RAC1:GTP
producedByEvent	[Reaction:R-CEL-5218850] VAV exchanges GTP for GDP on RAC1, activating it - Caenorhabditis elegans [Reaction:R-CEL-5357472] PAK1-3 autophosphorylates - Caenorhabditis elegans
schemaClass	Complex
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-5218784
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-CEL-5357472] PAK1-3 autophosphorylates [Reaction:R-CEL-5218850] VAV exchanges GTP for GDP on RAC1, activating it
(input)	[Reaction:R-CEL-5357483] RAC1 binds PAK1-3
(hasComponent)	[Complex:R-CEL-5357447] 2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] [Complex:R-CEL-5357487] p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane]
(inferredTo)	[Complex:R-HSA-5218784] p-VAV family:PIP3:RAC1:GTP [plasma membrane]