Reactome | Class C/3 (Metabotropic glutamate/pheromone receptors)

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Class C/3 (Metabotropic glutamate/pheromone receptors) Show undefined attributes

authored	[InstanceEdit:420459] Jassal, Bijay, 2009-05-12
created	[InstanceEdit:420459] Jassal, Bijay, 2009-05-12
dbId	420499
displayName	Class C/3 (Metabotropic glutamate/pheromone receptors)
edited	[InstanceEdit:420459] Jassal, Bijay, 2009-05-12
eventOf	[Pathway:R-HSA-500792] GPCR ligand binding - Homo sapiens
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-373075] Metabotropic glutamate receptors bind glutamate - Homo sapiens [Reaction:R-HSA-420724] CASR binds Ca2+ - Homo sapiens [Reaction:R-HSA-9703895] CASR binds CASR agonists - Homo sapiens [Reaction:R-HSA-420739] GPRC6A can bind L-alpha amino acids and calcium - Homo sapiens [Reaction:R-HSA-420688] GABAB heterodimeric receptor binds GABA - Homo sapiens [Reaction:R-HSA-444705] T1R1/T1R3 dimer is the umami taste receptor - Homo sapiens [Reaction:R-HSA-444606] T1R2/T1R3 dimer is a sweet taste receptor - Homo sapiens [Reaction:R-HSA-3296233] T2Rs bind bitter-tasting compounds - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2022-06-09
literatureReference	[LiteratureReference:419862] Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors [LiteratureReference:420701] Structure, pharmacology and therapeutic prospects of family C G-protein coupled receptors
maxDepth	2
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	Class C/3 (Metabotropic glutamate/pheromone receptors)
orthologousEvent	[Pathway:R-DDI-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Dictyostelium discoideum [Pathway:R-CEL-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Caenorhabditis elegans [Pathway:R-DME-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Drosophila melanogaster [Pathway:R-GGA-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Gallus gallus [Pathway:R-XTR-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Xenopus tropicalis [Pathway:R-DRE-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Danio rerio [Pathway:R-SSC-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Sus scrofa [Pathway:R-BTA-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Bos taurus [Pathway:R-CFA-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Canis familiaris [Pathway:R-RNO-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Rattus norvegicus [Pathway:R-MMU-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Mus musculus
releaseDate	2009-06-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:422381] D'Eustachio, P, 2009-05-29 07:44:22
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-420499
summation	[Summation:420689] The class C G-protein-coupled receptors are a class of G-pro...
updateTrackers	[UpdateTracker:9789790] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v37:[modifyText] [UpdateTracker:9787444] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v45:[addHasEvent] [UpdateTracker:9776601] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v75:[updateContainedRLE] [UpdateTracker:9786568] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v49:[modifyText] [UpdateTracker:9774689] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v81:[addHasEvent] [UpdateTracker:9780247] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v63:[updateContainedRLE] [UpdateTracker:9791100] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v32:[addHasEvent]

Referrals

(updatedInstance)

[UpdateTracker:9789790] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v37:[modifyText]
[UpdateTracker:9787444] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v45:[addHasEvent]
[UpdateTracker:9776601] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v75:[updateContainedRLE]
[UpdateTracker:9786568] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v49:[modifyText]
[UpdateTracker:9774689] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v81:[addHasEvent]
[UpdateTracker:9780247] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v63:[updateContainedRLE]
[UpdateTracker:9791100] Update Tracker - [Pathway:420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - v32:[addHasEvent]

(hasEvent)

[Pathway:R-HSA-500792] GPCR ligand binding

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