Reactome | Class C/3 (Metabotropic glutamate/pheromone receptors)

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Class C/3 (Metabotropic glutamate/pheromone receptors) Show undefined attributes

created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10648868
displayName	Class C/3 (Metabotropic glutamate/pheromone receptors)
eventOf	[Pathway:R-DRE-500792] GPCR ligand binding - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DRE-373075] Metabotropic glutamate receptors bind glutamate - Danio rerio [Reaction:R-DRE-420739] GPRC6A can bind L-alpha amino acids and calcium - Danio rerio [Reaction:R-DRE-444705] T1R1/T1R3 dimer is the umami taste receptor - Danio rerio [Reaction:R-DRE-444606] T1R2/T1R3 dimer is a sweet taste receptor - Danio rerio [Reaction:R-DRE-3296233] T2Rs bind bitter-tasting compounds - Danio rerio
inferredFrom	[Pathway:R-HSA-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Class C/3 (Metabotropic glutamate/pheromone receptors)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68323] Danio rerio
stId	R-DRE-420499
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DRE-500792] GPCR ligand binding
(inferredTo)	[Pathway:R-HSA-420499] Class C/3 (Metabotropic glutamate/pheromone receptors)

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