Reactome | Beta-oxidation of very long chain fatty acids

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Beta-oxidation of very long chain fatty acids Show undefined attributes

authored	[InstanceEdit:398115] D'Eustachio, P, 2009-03-16 18:50:14
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:390243] D'Eustachio, P, 2009-01-23 17:38:45
dbId	390247
displayName	Beta-oxidation of very long chain fatty acids
edited	[InstanceEdit:398202] D'Eustachio, P, 2009-03-18 13:33:40
eventOf	[Pathway:R-HSA-390918] Peroxisomal lipid metabolism - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:262733] fatty acid beta-oxidation using acyl-CoA oxidase
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-390393] Peroxisomal uptake of very long-chain fatty acyl CoA - Homo sapiens [Reaction:R-HSA-9914143] SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH - Homo sapiens [Reaction:R-HSA-6809808] ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA - Homo sapiens [Reaction:R-HSA-390256] ACOX1 oxidizes C26:0 CoA - Homo sapiens [Reaction:R-HSA-390252] HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA - Homo sapiens [Reaction:R-HSA-6809263] EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA - Homo sapiens [Reaction:R-HSA-390251] HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA - Homo sapiens [Reaction:R-HSA-6809264] EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA - Homo sapiens [Reaction:R-HSA-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Homo sapiens [BlackBoxEvent:R-HSA-390302] Beta-oxidation of tetradecenoyl-CoA to octanoyl-CoA - Homo sapiens [Reaction:R-HSA-977317] malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome - Homo sapiens [Reaction:R-HSA-6786720] DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA - Homo sapiens [Reaction:R-HSA-5690042] Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2017-06-22
literatureReference	[LiteratureReference:389650] Biochemistry of mammalian peroxisomes revisited
maxDepth	2
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Beta-oxidation of very long chain fatty acids
orthologousEvent	[Pathway:R-SCE-390247] Beta-oxidation of very long chain fatty acids - Saccharomyces cerevisiae [Pathway:R-DDI-390247] Beta-oxidation of very long chain fatty acids - Dictyostelium discoideum [Pathway:R-CEL-390247] Beta-oxidation of very long chain fatty acids - Caenorhabditis elegans [Pathway:R-DME-390247] Beta-oxidation of very long chain fatty acids - Drosophila melanogaster [Pathway:R-GGA-390247] Beta-oxidation of very long chain fatty acids - Gallus gallus [Pathway:R-XTR-390247] Beta-oxidation of very long chain fatty acids - Xenopus tropicalis [Pathway:R-DRE-390247] Beta-oxidation of very long chain fatty acids - Danio rerio [Pathway:R-SSC-390247] Beta-oxidation of very long chain fatty acids - Sus scrofa [Pathway:R-BTA-390247] Beta-oxidation of very long chain fatty acids - Bos taurus [Pathway:R-CFA-390247] Beta-oxidation of very long chain fatty acids - Canis familiaris [Pathway:R-RNO-390247] Beta-oxidation of very long chain fatty acids - Rattus norvegicus [Pathway:R-MMU-390247] Beta-oxidation of very long chain fatty acids - Mus musculus
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:392190] Jassal, Bijay, 2009-02-27 [InstanceEdit:9917333] Hill, David P, 2024-08-02
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-390247
summation	[Summation:390236] Linear fatty acids containing more than 18 carbons are broke...
updateTrackers	[UpdateTracker:9781924] Update Tracker - [Pathway:390247] Beta-oxidation of very long chain fatty acids - v60:[addHasEvent] [UpdateTracker:9781492] Update Tracker - [Pathway:390247] Beta-oxidation of very long chain fatty acids - v61:[removeHasEvent] [UpdateTracker:9919470] Update Tracker - [Pathway:390247] Beta-oxidation of very long chain fatty acids - v90:[removeHasEvent]

Referrals

(updatedInstance)	[UpdateTracker:9781924] Update Tracker - [Pathway:390247] Beta-oxidation of very long chain fatty acids - v60:[addHasEvent] [UpdateTracker:9781492] Update Tracker - [Pathway:390247] Beta-oxidation of very long chain fatty acids - v61:[removeHasEvent] [UpdateTracker:9919470] Update Tracker - [Pathway:390247] Beta-oxidation of very long chain fatty acids - v90:[removeHasEvent]
(hasEvent)	[Pathway:R-HSA-390918] Peroxisomal lipid metabolism

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