Reactome | 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA

Schema > Reaction > Entries

3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA Show undefined attributes

authored	[InstanceEdit:398115] D'Eustachio, P, 2009-03-16 18:50:14
catalystActivity	[CatalystActivity:390234] acetyl-CoA C-acyltransferase activity of ACAA1 [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:390243] D'Eustachio, P, 2009-01-23 17:38:45
crossReference	[DatabaseIdentifier:12667718] RHEA:78641 [DatabaseIdentifier:9914125] RHEA:78641
dbId	390250
displayName	3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA
edited	[InstanceEdit:398202] D'Eustachio, P, 2009-03-18 13:33:40
eventOf	[Pathway:R-HSA-390247] Beta-oxidation of very long chain fatty acids - Homo sapiens
followingEvent	[Reaction:R-HSA-390291] acetyl-CoA + carnitine => acetylcarnitine + CoASH - Homo sapiens [Reaction:R-HSA-390304] acetyl-CoA + H2O => acetate + CoASH + H+ - Homo sapiens [BlackBoxEvent:R-HSA-390302] Beta-oxidation of tetradecenoyl-CoA to octanoyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-390241] 3-ketohexacosanoyl-CoA [peroxisomal matrix] [SimpleEntity:R-ALL-193514] CoA-SH [peroxisomal matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:390257] Characterization of the gene encoding human peroxisomal 3-oxoacyl-CoA thiolase (ACAA). No large DNA rearrangement in a thiolase-deficient patient
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA 3-oxohexacosanoyl-CoA + CoA => acetyl-CoA + tetracosanoyl-CoA
orthologousEvent	[Reaction:R-SCE-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Saccharomyces cerevisiae [Reaction:R-DDI-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Dictyostelium discoideum [Reaction:R-GGA-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Gallus gallus [Reaction:R-XTR-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Xenopus tropicalis [Reaction:R-DRE-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Danio rerio [Reaction:R-SSC-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Sus scrofa [Reaction:R-BTA-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Bos taurus [Reaction:R-CFA-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Canis familiaris [Reaction:R-RNO-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Rattus norvegicus [Reaction:R-MMU-390250] 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA - Mus musculus
output	[SimpleEntity:R-ALL-353123] Ac-CoA [peroxisomal matrix] [SimpleEntity:R-ALL-390246] tetracosanoyl-CoA [peroxisomal matrix]
precedingEvent	[Reaction:R-HSA-390251] HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA - Homo sapiens [Reaction:R-HSA-6809264] EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA - Homo sapiens
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:392190] Jassal, Bijay, 2009-02-27
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-390250
summation	[Summation:390233] Peroxisomal ACAA1 catalyzes the reaction of 3-ketohexacosano...

Referrals

(precedingEvent)	[Reaction:R-HSA-390291] acetyl-CoA + carnitine => acetylcarnitine + CoASH [Reaction:R-HSA-390304] acetyl-CoA + H2O => acetate + CoASH + H+ [BlackBoxEvent:R-HSA-390302] Beta-oxidation of tetradecenoyl-CoA to octanoyl-CoA
(hasEvent)	[Pathway:R-HSA-390247] Beta-oxidation of very long chain fatty acids