Reactome | Phosphorylated IRE1 dimer binds ADP

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Phosphorylated IRE1 dimer binds ADP Show undefined attributes

authored	[InstanceEdit:422550] May, B, 2009-06-02 00:51:49
category	binding
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:381159] May, B, 2008-11-19 16:17:44
dbId	381116
displayName	Phosphorylated IRE1 dimer binds ADP
edited	[InstanceEdit:422550] May, B, 2009-06-02 00:51:49
eventOf	[Pathway:R-HSA-381070] IRE1alpha activates chaperones - Homo sapiens
figure	[Figure:381187] /figures/UPR-IRE1dimerization.jpg
followingEvent	[BlackBoxEvent:R-HSA-425923] IRE1alpha hydrolyzes Xbp1 mRNA and Xbp1 mRNA is spliced - Homo sapiens
inferredFrom	[Reaction:R-SCE-535524] Phosphorylated Ire1 Dimer Binds ADP - Saccharomyces cerevisiae
input	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-381154] p-S724-IRE1 dimer [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phosphorylated IRE1 dimer binds ADP
output	[Complex:R-HSA-381078] p-S724-IRE1 dimer:ADP [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-381091] IRE1 dimer autophosphorylates - Homo sapiens
releaseDate	2009-06-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:387470] D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31 [InstanceEdit:638652] Urano, F, 2010-04-30
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-381116
summation	[Summation:381032] Phosphorylation of the C-terminal region causes a loop in th...
updateTrackers	[UpdateTracker:9790465] Update Tracker - [Reaction:381116] Phosphorylated IRE1 dimer binds ADP - v33:[removeLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9790465] Update Tracker - [Reaction:381116] Phosphorylated IRE1 dimer binds ADP - v33:[removeLiteratureReference]
(hasEvent)	[Pathway:R-HSA-381070] IRE1alpha activates chaperones
(precedingEvent)	[BlackBoxEvent:R-HSA-425923] IRE1alpha hydrolyzes Xbp1 mRNA and Xbp1 mRNA is spliced
(inferredTo)	[Reaction:R-SCE-535524] Phosphorylated Ire1 Dimer Binds ADP

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