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Schema
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Pathway
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Entries
Mitochondrial tRNA aminoacylation
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authored
[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
compartment
[Compartment:5460] mitochondrial matrix
created
[InstanceEdit:379702] D'Eustachio, P, 2008-11-04 23:29:06
dbId
379726
displayName
Mitochondrial tRNA aminoacylation
edited
[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
eventOf
[Pathway:R-HSA-379724] tRNA Aminoacylation - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:18542] tRNA aminoacylation for protein translation
hasDiagram
false
hasEHLD
false
hasEvent
[Reaction:R-HSA-380177] alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380224] arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380227] asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380229] aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380158] cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380216] glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380241] glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380240] glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380234] histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380176] isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380200] leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380233] lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380157] methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380203] phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380198] proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380239] serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380201] threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380222] tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380170] tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-380199] valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate - Homo sapiens
[Reaction:R-HSA-449937] pyrophosphate + H2O => 2 orthophosphate [mitochondrial] - Homo sapiens
isInDisease
false
isInferred
false
lastUpdatedDate
2016-12-21
literatureReference
[LiteratureReference:1449549] Mitochondrial tRNA import: are there distinct mechanisms?
maxDepth
2
modified
[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name
Mitochondrial tRNA aminoacylation
orthologousEvent
[Pathway:R-MMU-379726] Mitochondrial tRNA aminoacylation - Mus musculus
[Pathway:R-RNO-379726] Mitochondrial tRNA aminoacylation - Rattus norvegicus
[Pathway:R-CFA-379726] Mitochondrial tRNA aminoacylation - Canis familiaris
[Pathway:R-BTA-379726] Mitochondrial tRNA aminoacylation - Bos taurus
[Pathway:R-SSC-379726] Mitochondrial tRNA aminoacylation - Sus scrofa
[Pathway:R-DRE-379726] Mitochondrial tRNA aminoacylation - Danio rerio
[Pathway:R-XTR-379726] Mitochondrial tRNA aminoacylation - Xenopus tropicalis
[Pathway:R-GGA-379726] Mitochondrial tRNA aminoacylation - Gallus gallus
[Pathway:R-DME-379726] Mitochondrial tRNA aminoacylation - Drosophila melanogaster
[Pathway:R-CEL-379726] Mitochondrial tRNA aminoacylation - Caenorhabditis elegans
[Pathway:R-DDI-379726] Mitochondrial tRNA aminoacylation - Dictyostelium discoideum
[Pathway:R-SPO-379726] Mitochondrial tRNA aminoacylation - Schizosaccharomyces pombe
[Pathway:R-SCE-379726] Mitochondrial tRNA aminoacylation - Saccharomyces cerevisiae
[Pathway:R-PFA-379726] Mitochondrial tRNA aminoacylation - Plasmodium falciparum
releaseDate
2008-12-17
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:387428] Antonellis, A, 2008-12-02 16:58:45
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-379726
summation
[Summation:379733] Mitochondrial tRNA synthetases act in the mitochondrial matr...
updateTrackers
[UpdateTracker:9782253] Update Tracker - [Pathway:379726] Mitochondrial tRNA aminoacylation - v59:[updateContainedRLE]
[UpdateTracker:9789645] Update Tracker - [Pathway:379726] Mitochondrial tRNA aminoacylation - v37:[updateContainedRLE]
[UpdateTracker:9791631] Update Tracker - [Pathway:379726] Mitochondrial tRNA aminoacylation - v28:[updateContainedRLE]
[UpdateTracker:9789200] Update Tracker - [Pathway:379726] Mitochondrial tRNA aminoacylation - v38:[addLiteratureReference, modifyText]
[UpdateTracker:9790633] Update Tracker - [Pathway:379726] Mitochondrial tRNA aminoacylation - v33:[addHasEvent, updateContainedRLE]
Referrals
(hasEvent)
[Pathway:R-HSA-379724] tRNA Aminoacylation
(updatedInstance)
[UpdateTracker:9782253] Update Tracker - [Pathway:379726] Mitochondrial tRNA aminoacylation - v59:[updateContainedRLE]
[UpdateTracker:9789645] Update Tracker - [Pathway:379726] Mitochondrial tRNA aminoacylation - v37:[updateContainedRLE]
[UpdateTracker:9791631] Update Tracker - [Pathway:379726] Mitochondrial tRNA aminoacylation - v28:[updateContainedRLE]
[UpdateTracker:9789200] Update Tracker - [Pathway:379726] Mitochondrial tRNA aminoacylation - v38:[addLiteratureReference, modifyText]
[UpdateTracker:9790633] Update Tracker - [Pathway:379726] Mitochondrial tRNA aminoacylation - v33:[addHasEvent, updateContainedRLE]
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