Reactome | tRNA Aminoacylation

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tRNA Aminoacylation Show undefined attributes

authored	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
created	[InstanceEdit:379702] D'Eustachio, P, 2008-11-04 23:29:06
dbId	379724
displayName	tRNA Aminoacylation
doi	10.3180/REACT_15482.1
edited	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
eventOf	[Pathway:R-HSA-72766] Translation - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:18542] tRNA aminoacylation for protein translation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-379716] Cytosolic tRNA aminoacylation - Homo sapiens [Pathway:R-HSA-379726] Mitochondrial tRNA aminoacylation - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2016-12-21
literatureReference	[LiteratureReference:380811] Aminoacyl tRNA synthetases and their connections to disease [LiteratureReference:380822] Enzyme hyperspecificity. Rejection of threonine by the valyl-tRNA synthetase by misacylation and hydrolytic editing [LiteratureReference:389203] Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers [LiteratureReference:380815] Mechanism of aminoacylation of tRNA. Proof of the aminoacyl adenylate pathway for the isoleucyl- and tyrosyl-tRNA synthetases from Escherichia coli K12 [LiteratureReference:380821] Purification and properties of isoleucyl ribonucleic acid synthetase from Escherichia coli [LiteratureReference:380808] Structural relationships and the classification of aminoacyl-tRNA synthetases [LiteratureReference:380810] The role of aminoacyl-tRNA synthetases in genetic diseases [LiteratureReference:380812] Transfer ribonucleic acid-induced hydrolysis of valyladenylate bound to isoleucyl ribonucleic acid synthetase
maxDepth	3
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	tRNA Aminoacylation
orthologousEvent	[Pathway:R-PFA-379724] tRNA Aminoacylation - Plasmodium falciparum [Pathway:R-SCE-379724] tRNA Aminoacylation - Saccharomyces cerevisiae [Pathway:R-SPO-379724] tRNA Aminoacylation - Schizosaccharomyces pombe [Pathway:R-DDI-379724] tRNA Aminoacylation - Dictyostelium discoideum [Pathway:R-CEL-379724] tRNA Aminoacylation - Caenorhabditis elegans [Pathway:R-DME-379724] tRNA Aminoacylation - Drosophila melanogaster [Pathway:R-GGA-379724] tRNA Aminoacylation - Gallus gallus [Pathway:R-XTR-379724] tRNA Aminoacylation - Xenopus tropicalis [Pathway:R-DRE-379724] tRNA Aminoacylation - Danio rerio [Pathway:R-SSC-379724] tRNA Aminoacylation - Sus scrofa [Pathway:R-BTA-379724] tRNA Aminoacylation - Bos taurus [Pathway:R-CFA-379724] tRNA Aminoacylation - Canis familiaris [Pathway:R-RNO-379724] tRNA Aminoacylation - Rattus norvegicus [Pathway:R-MMU-379724] tRNA Aminoacylation - Mus musculus
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:387428] Antonellis, A, 2008-12-02 16:58:45
revised	[InstanceEdit:389225] D'Eustachio, P, 2008-12-23 21:40:28
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-379724
summation	[Summation:379723] tRNA synthetases catalyze the ligation of tRNAs to their cog...
updateTrackers	[UpdateTracker:9782084] Update Tracker - [Pathway:379724] tRNA Aminoacylation - v59:[updateIndirectRLE] [UpdateTracker:9791602] Update Tracker - [Pathway:379724] tRNA Aminoacylation - v28:[modifyText, updateIndirectRLE] [UpdateTracker:9789387] Update Tracker - [Pathway:379724] tRNA Aminoacylation - v38:[addLiteratureReference, updateContainedPathway] [UpdateTracker:9789628] Update Tracker - [Pathway:379724] tRNA Aminoacylation - v37:[updateIndirectRLE] [UpdateTracker:9790536] Update Tracker - [Pathway:379724] tRNA Aminoacylation - v33:[updateContainedPathway, updateIndirectRLE]

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[Pathway:R-HSA-72766] Translation

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