Reactome | lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate

Schema > Reaction > Entries

lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate Show undefined attributes

authored	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
catalystActivity	[CatalystActivity:379597] lysine-tRNA ligase activity of KARS dimer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:380210] D'Eustachio, P, 2008-11-08 17:23:03
dbId	380233
displayName	lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
edited	[InstanceEdit:386989] D'Eustachio, P, 2008-11-29 15:41:00
eventOf	[Pathway:R-HSA-379726] Mitochondrial tRNA aminoacylation - Homo sapiens
input	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [SimpleEntity:R-ALL-29444] L-Lys [mitochondrial matrix] [GenomeEncodedEntity:R-HSA-379747] tRNA(Lys) [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:379986] Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate
output	[SimpleEntity:R-ALL-159448] AMP [mitochondrial matrix] [GenomeEncodedEntity:R-HSA-379795] Lys-tRNA(Lys) [mitochondrial matrix] [SimpleEntity:R-ALL-159450] PPi [mitochondrial matrix]
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:387428] Antonellis, A, 2008-12-02 16:58:45
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-380233
summation	[Summation:380193] KARS (mitochondrial lysyl tRNA synthetase) catalyzes the rea...

Referrals

(hasEvent)

[Pathway:R-HSA-379726] Mitochondrial tRNA aminoacylation

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