Reactome | Bradykinin receptors B1 and B2 bind to bradykinin

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Bradykinin receptors B1 and B2 bind to bradykinin Show undefined attributes

authored	[InstanceEdit:375275] Jassal, Bijay, 2008-08-21
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:374359] Jassal, Bijay, 2008-07-29
dbId	374331
displayName	Bradykinin receptors B1 and B2 bind to bradykinin
edited	[InstanceEdit:375493] D'Eustachio, P, 2008-09-01 11:58:31
eventOf	[Pathway:R-HSA-375276] Peptide ligand-binding receptors - Homo sapiens
followingEvent	[Reaction:R-HSA-749448] Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq - Homo sapiens [Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-158344] Bradykinin [extracellular region] [DefinedSet:R-HSA-374323] Bradykinin receptor [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:374346] Isolation and identification of hydroxyproline analogues of bradykinin in human urine [LiteratureReference:374350] Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor [LiteratureReference:374361] Expression cloning of a human B1 bradykinin receptor [LiteratureReference:374364] Bradykinin, a hypotensive and smooth muscle stimulating factor released from plasma globulin by snake venoms and by trypsin
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Bradykinin receptors B1 and B2 bind to bradykinin
orthologousEvent	[Reaction:R-GGA-374331] Bradykinin receptors B1 and B2 bind to bradykinin - Gallus gallus [Reaction:R-BTA-374331] Bradykinin receptors B1 and B2 bind to bradykinin - Bos taurus [Reaction:R-CFA-374331] Bradykinin receptors B1 and B2 bind to bradykinin - Canis familiaris [Reaction:R-RNO-374331] Bradykinin receptors B1 and B2 bind to bradykinin - Rattus norvegicus [Reaction:R-MMU-374331] Bradykinin receptors B1 and B2 bind to bradykinin - Mus musculus
output	[Complex:R-HSA-374321] Bradykinin receptor:Bradykinin [plasma membrane]
releaseDate	2008-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:375494] Bockaert, J, 2008-09-01 12:04:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-374331
summation	[Summation:374329] Bradykinin (Rocha e Silva M, et al, 1949) is a 9 amino-acid ...

Referrals

(hasEvent)	[Pathway:R-HSA-375276] Peptide ligand-binding receptors
(precedingEvent)	[Reaction:R-HSA-749448] Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq [Reaction:R-HSA-749456] Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi