Reactome | GRB2:SOS provides linkage to MAPK signaling for Integrins

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GRB2:SOS provides linkage to MAPK signaling for Integrins Show undefined attributes

authored	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
created	[InstanceEdit:354193] Garapati, P V, 2008-06-16 17:13:06
crossReference	[DatabaseIdentifier:12325424] BioModels Database:BIOMD0000000255 [DatabaseIdentifier:12325370] BioModels Database:BIOMD0000000653 [DatabaseIdentifier:12325372] BioModels Database:BIOMD0000000656 [DatabaseIdentifier:12325386] BioModels Database:BIOMD0000000338 [DatabaseIdentifier:12325388] BioModels Database:BIOMD0000000340 [DatabaseIdentifier:12325374] BioModels Database:BIOMD0000000648 [DatabaseIdentifier:12325476] BioModels Database:BIOMD0000000466 [DatabaseIdentifier:12325430] BioModels Database:BIOMD0000000175 [DatabaseIdentifier:12325378] BioModels Database:BIOMD0000000655 [DatabaseIdentifier:12325380] BioModels Database:BIOMD0000000652 [DatabaseIdentifier:12325398] BioModels Database:BIOMD0000000339 [DatabaseIdentifier:12325346] BioModels Database:BIOMD0000000883 [DatabaseIdentifier:12325480] BioModels Database:BIOMD0000000468 [DatabaseIdentifier:12325442] BioModels Database:BIOMD0000000399 [DatabaseIdentifier:12325444] BioModels Database:BIOMD0000000019 [DatabaseIdentifier:12325446] BioModels Database:BIOMD0000000424 [DatabaseIdentifier:12325382] BioModels Database:BIOMD0000000654
dbId	354194
displayName	GRB2:SOS provides linkage to MAPK signaling for Integrins
edited	[InstanceEdit:354203] Garapati, P V, 2008-06-16 17:32:15
eventOf	[Pathway:R-HSA-354192] Integrin signaling - Homo sapiens
figure	[Figure:372833] /figures/GPIIbII3Integrin-MAPK.png
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-354087] Recruitment of GRB2 to p-PTK2 - Homo sapiens [Reaction:R-HSA-354165] Interaction of SOS with GRB2 bound to FADK1 - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:354100] The structural basis of localization and signaling by the focal adhesion targeting domain [LiteratureReference:354156] Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase [LiteratureReference:354148] Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events
modified	[InstanceEdit:12325341] Wright, Adam, 2024-02-14
name	GRB2:SOS provides linkage to MAPK signaling for Integrins
orthologousEvent	[Pathway:R-CEL-354194] GRB2:SOS provides linkage to MAPK signaling for Integrins - Caenorhabditis elegans [Pathway:R-GGA-354194] GRB2:SOS provides linkage to MAPK signaling for Integrins - Gallus gallus [Pathway:R-SSC-354194] GRB2:SOS provides linkage to MAPK signaling for Integrins - Sus scrofa [Pathway:R-BTA-354194] GRB2:SOS provides linkage to MAPK signaling for Integrins - Bos taurus [Pathway:R-CFA-354194] GRB2:SOS provides linkage to MAPK signaling for Integrins - Canis familiaris [Pathway:R-RNO-354194] GRB2:SOS provides linkage to MAPK signaling for Integrins - Rattus norvegicus [Pathway:R-MMU-354194] GRB2:SOS provides linkage to MAPK signaling for Integrins - Mus musculus
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:377695] Shattil, SJ, 2008-09-16 06:21:39
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-354194
summation	[Summation:373157] Integrin signaling is linked to the MAP kinase pathway by re...

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[Pathway:R-HSA-354192] Integrin signaling

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