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Reaction
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Entries
SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine
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authored
[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
catalystActivity
[CatalystActivity:352361] amino acid transmembrane transporter activity of SLC1A4 [plasma membrane]
category
transition
compartment
[Compartment:876] plasma membrane
created
[InstanceEdit:352351] D'Eustachio, P, 2008-06-02 18:13:12
crossReference
[DatabaseIdentifier:11880231] Rhea:29283
dbId
352364
displayName
SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine
edited
[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
eventOf
[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane - Homo sapiens
input
[DefinedSet:R-ALL-352355] alanine, serine, threonine, or cysteine [cytosol]
[SimpleEntity:R-ALL-352036] L-Ala [extracellular region]
[SimpleEntity:R-ALL-83910] Na+ [cytosol]
[SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:352345] ASCT-1 is a neutral amino acid exchanger with chloride channel activity
[LiteratureReference:352362] Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family
[LiteratureReference:352348] Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters
modified
[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name
SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine
orthologousEvent
[Reaction:R-CEL-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Caenorhabditis elegans
[Reaction:R-DME-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Drosophila melanogaster
[Reaction:R-GGA-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Gallus gallus
[Reaction:R-XTR-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Xenopus tropicalis
[Reaction:R-DRE-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Danio rerio
[Reaction:R-SSC-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Sus scrofa
[Reaction:R-BTA-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Bos taurus
[Reaction:R-CFA-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Canis familiaris
[Reaction:R-RNO-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Rattus norvegicus
[Reaction:R-MMU-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Mus musculus
output
[DefinedSet:R-ALL-352359] alanine, serine, threonine, or cysteine [extracellular region]
[SimpleEntity:R-ALL-29432] L-Ala [cytosol]
[SimpleEntity:R-ALL-83910] Na+ [cytosol]
[SimpleEntity:R-ALL-74113] Na+ [extracellular region]
releaseDate
2008-06-30
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:352498] Jassal, Bijay, 2008-06-03
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-352364
summation
[Summation:352358] SLC1A4, associated with the plasma membrane, mediates the ex...
Referrals
(hasEvent)
[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane
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