Reactome | SLC38A2 (ATA2)-mediated uptake of neutral amino acids

Schema > Reaction > Entries

SLC38A2 (ATA2)-mediated uptake of neutral amino acids Show undefined attributes

authored	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
catalystActivity	[CatalystActivity:352086] amino acid transmembrane transporter activity of SLC38A2 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:352121] D'Eustachio, P, 2008-05-30 18:55:49
crossReference	[DatabaseIdentifier:12667957] RHEA:29263 [DatabaseIdentifier:12667958] RHEA:68228 [DatabaseIdentifier:12667538] RHEA:68236 [DatabaseIdentifier:12667961] RHEA:28967 [DatabaseIdentifier:12667955] RHEA:69999 [DatabaseIdentifier:12667962] RHEA:68240 [DatabaseIdentifier:9956837] RHEA:68238 [DatabaseIdentifier:12667960] RHEA:71383 [DatabaseIdentifier:12667954] RHEA:29283 [DatabaseIdentifier:12667959] RHEA:29575 [DatabaseIdentifier:9956846] RHEA:29285 [DatabaseIdentifier:9956843] RHEA:29577 [DatabaseIdentifier:9956819] RHEA:71385 [DatabaseIdentifier:9960018] RHEA:68242 [DatabaseIdentifier:9960021] RHEA:68230 [DatabaseIdentifier:9956831] RHEA:28969 [DatabaseIdentifier:9956823] RHEA:29265 [DatabaseIdentifier:9956844] RHEA:70001
dbId	352108
displayName	SLC38A2 (ATA2)-mediated uptake of neutral amino acids
edited	[InstanceEdit:352382] D'Eustachio, P, 2008-06-02 20:10:30
eventOf	[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane - Homo sapiens
input	[DefinedSet:R-ALL-352091] ligands of SLC38A2 [extracellular region] [SimpleEntity:R-ALL-74113] Na+ [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:352090] Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	SLC38A2 (ATA2)-mediated uptake of neutral amino acids
negativePrecedingEvent	[NegativePrecedingEvent:9963233] Futile Cycle: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine [NegativePrecedingEvent:9963202] Futile Cycle: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine [NegativePrecedingEvent:9963272] Futile Cycle: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine [NegativePrecedingEvent:9963308] Futile Cycle: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane [NegativePrecedingEvent:9963321] Futile Cycle: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane [NegativePrecedingEvent:9963384] Futile Cycle: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu
orthologousEvent	[Reaction:R-MMU-352108] SLC38A2 (ATA2)-mediated uptake of neutral amino acids - Mus musculus [Reaction:R-RNO-352108] SLC38A2 (ATA2)-mediated uptake of neutral amino acids - Rattus norvegicus [Reaction:R-CFA-352108] SLC38A2 (ATA2)-mediated uptake of neutral amino acids - Canis familiaris [Reaction:R-BTA-352108] SLC38A2 (ATA2)-mediated uptake of neutral amino acids - Bos taurus [Reaction:R-SSC-352108] SLC38A2 (ATA2)-mediated uptake of neutral amino acids - Sus scrofa [Reaction:R-DRE-352108] SLC38A2 (ATA2)-mediated uptake of neutral amino acids - Danio rerio [Reaction:R-XTR-352108] SLC38A2 (ATA2)-mediated uptake of neutral amino acids - Xenopus tropicalis [Reaction:R-GGA-352108] SLC38A2 (ATA2)-mediated uptake of neutral amino acids - Gallus gallus
output	[DefinedSet:R-ALL-352088] ligands of SLC38A2 [cytosol] [SimpleEntity:R-ALL-83910] Na+ [cytosol]
precedingEvent	[Reaction:R-HSA-352364] SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine - Homo sapiens
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:352498] Jassal, Bijay, 2008-06-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-352108
summation	[Summation:352124] SLC38A2 (ATA2), associated with the plasma membrane, mediate...

Referrals

(precedingEvent)

[NegativePrecedingEvent:9963330] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids
[NegativePrecedingEvent:9963347] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids
[NegativePrecedingEvent:9963343] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids
[NegativePrecedingEvent:9963331] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids
[NegativePrecedingEvent:9963356] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids
[NegativePrecedingEvent:9963365] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids
[NegativePrecedingEvent:9963368] Futile Cycle: SLC38A2 (ATA2)-mediated uptake of neutral amino acids

(hasEvent)

[Pathway:R-HSA-352230] Amino acid transport across the plasma membrane

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