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Entries
SUMOylation of DNA damage response and repair proteins
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authored
[InstanceEdit:3065680] May, B, 2013-02-06
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:3108223] May, B, 2013-02-10
dbId
3108214
displayName
SUMOylation of DNA damage response and repair proteins
edited
[InstanceEdit:3065680] May, B, 2013-02-06
eventOf
[Pathway:R-HSA-3108232] SUMO E3 ligases SUMOylate target proteins - Homo sapiens
hasDiagram
true
hasEHLD
false
hasEvent
[Reaction:R-HSA-4568914] SUMOylation of BLM with SUMO2,3 - Homo sapiens
[Reaction:R-HSA-2997709] PIAS1,4 SUMOylates BRCA1 with SUMO1 - Homo sapiens
[Reaction:R-HSA-2997616] PIAS1,4 SUMOylates BRCA1 with SUMO2,3 - Homo sapiens
[Reaction:R-HSA-4570463] CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 - Homo sapiens
[Reaction:R-HSA-3108212] SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 - Homo sapiens
[Reaction:R-HSA-4551724] PIAS4 SUMOylates HERC2 with SUMO1 - Homo sapiens
[Reaction:R-HSA-4570554] SUMOylation of MDC1 with SUMO1 - Homo sapiens
[Reaction:R-HSA-4570553] SUMOylation of MDC1 with SUMO2,3 - Homo sapiens
[Reaction:R-HSA-4551604] PIAS4 SUMOylates PARP1 with SUMO1 - Homo sapiens
[Reaction:R-HSA-4551768] PIAS4 SUMOylates PARP1 with SUMO2,3 - Homo sapiens
[Reaction:R-HSA-3000383] UBE2I, HDAC7 SUMOylate PML with SUMO1 - Homo sapiens
[Reaction:R-HSA-5228508] RANBP2 SUMOylates PML with SUMO1 - Homo sapiens
[Reaction:R-HSA-3000411] RANBP2 SUMOylates PML with SUMO2 - Homo sapiens
[Reaction:R-HSA-3000433] SUMOylation of PML with SUMO3 - Homo sapiens
[Reaction:R-HSA-4568863] SUMOylation of RAD52 with SUMO1 - Homo sapiens
[Reaction:R-HSA-4551661] PIAS4 SUMOylates RNF168 with SUMO1 - Homo sapiens
[Reaction:R-HSA-4551616] SUMOylation of RPA1 (RPA70) with SUMO2,3 - Homo sapiens
[Reaction:R-HSA-3000399] RANBP2 SUMOylates SP100 with SUMO1 - Homo sapiens
[Reaction:R-HSA-3000348] RANBP2 SUMOylates SP100 with SUMO2 - Homo sapiens
[Reaction:R-HSA-4551648] SUMOylation of TDG with SUMO1 - Homo sapiens
[Reaction:R-HSA-4551738] SUMOylation of TDG with SUMO2,3 - Homo sapiens
[Reaction:R-HSA-4568846] CDKN2A (p14-ARF) SUMOylates WRN with SUMO1 - Homo sapiens
[Reaction:R-HSA-4568848] PIAS1,2-1 SUMOylates XRCC4 with SUMO1 - Homo sapiens
[Reaction:R-HSA-4570528] SUMOylation of XPC with SUMO1 - Homo sapiens
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:4663793] Regulation of DNA damage responses by ubiquitin and SUMO
[LiteratureReference:4663772] Ubiquitin and SUMO in DNA repair at a glance
[LiteratureReference:4663756] The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks
[LiteratureReference:4663738] SUMOylation and de-SUMOylation in response to DNA damage
[LiteratureReference:5215905] Sumoylation: a regulatory protein modification in health and disease
[LiteratureReference:5225691] Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair
[LiteratureReference:5225688] It takes two to tango: Ubiquitin and SUMO in the DNA damage response
[LiteratureReference:5228438] Shared and unique properties of ubiquitin and SUMO interaction networks in DNA repair
[LiteratureReference:5677002] Sumoylation and the DNA damage response
[LiteratureReference:5676988] SUMO playing tag with ubiquitin
modified
[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name
SUMOylation of DNA damage response and repair proteins
orthologousEvent
[Pathway:R-MMU-3108214] SUMOylation of DNA damage response and repair proteins - Mus musculus
[Pathway:R-RNO-3108214] SUMOylation of DNA damage response and repair proteins - Rattus norvegicus
[Pathway:R-BTA-3108214] SUMOylation of DNA damage response and repair proteins - Bos taurus
[Pathway:R-SSC-3108214] SUMOylation of DNA damage response and repair proteins - Sus scrofa
[Pathway:R-DRE-3108214] SUMOylation of DNA damage response and repair proteins - Danio rerio
[Pathway:R-XTR-3108214] SUMOylation of DNA damage response and repair proteins - Xenopus tropicalis
[Pathway:R-GGA-3108214] SUMOylation of DNA damage response and repair proteins - Gallus gallus
[Pathway:R-DME-3108214] SUMOylation of DNA damage response and repair proteins - Drosophila melanogaster
[Pathway:R-CEL-3108214] SUMOylation of DNA damage response and repair proteins - Caenorhabditis elegans
[Pathway:R-DDI-3108214] SUMOylation of DNA damage response and repair proteins - Dictyostelium discoideum
[Pathway:R-SPO-3108214] SUMOylation of DNA damage response and repair proteins - Schizosaccharomyces pombe
[Pathway:R-SCE-3108214] SUMOylation of DNA damage response and repair proteins - Saccharomyces cerevisiae
[Pathway:R-PFA-3108214] SUMOylation of DNA damage response and repair proteins - Plasmodium falciparum
releaseDate
2015-03-19
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:5677000] Ferrari, Stefano, 2015-02-21
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-3108214
summation
[Summation:5225572] Several factors that participate in DNA damage response and ...
Referrals
(hasEvent)
[Pathway:R-HSA-3108232] SUMO E3 ligases SUMOylate target proteins
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