Reactome | p-T,2S-SMAD2,3:SMAD4 [nucleoplasm]

Schema > DefinedSet > Entries

p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-2176504] Ub-p-T-2S-SMAD2,3:SMAD4 [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-2176491] NEDD4L binds phosphorylated linker region of SMAD2/3 - Homo sapiens [Reaction:R-HSA-2179274] SMURF2 binds SMAD3 phosphorylated in the linker region - Homo sapiens
created	[InstanceEdit:2176486] Orlic-Milacic, M, 2012-04-02
dbId	2176487
displayName	p-T,2S-SMAD2,3:SMAD4 [nucleoplasm]
hasMember	[Complex:R-HSA-9736936] p-T,2S-SMAD2:p-T,2S-SMAD2:SMAD4 [nucleoplasm] - Homo sapiens [Complex:R-HSA-9736938] p-T,2S-SMAD2:p-T,2S-SMAD3:SMAD4 [nucleoplasm] - Homo sapiens [Complex:R-HSA-9736939] p-T,2S-SMAD3:p-T,2S-SMAD3:SMAD4 [nucleoplasm] - Homo sapiens
inDisease	false
inferredTo	[DefinedSet:R-MMU-2176487] p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] - Mus musculus [DefinedSet:R-RNO-2176487] p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] - Rattus norvegicus [DefinedSet:R-CFA-2176487] p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] - Canis familiaris [DefinedSet:R-BTA-2176487] p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] - Bos taurus [Complex:R-SSC-9736939] p-T,2S-SMAD3:p-T,2S-SMAD3:SMAD4 [nucleoplasm] - Sus scrofa [GenomeEncodedEntity:R-DRE-2176487] Ghost homologue of p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] - Danio rerio [Complex:R-XTR-9736936] p-T,2S-SMAD2:p-T,2S-SMAD2:SMAD4 [nucleoplasm] - Xenopus tropicalis [DefinedSet:R-GGA-2176487] p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] - Gallus gallus [DefinedSet:R-DME-2176487] p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] - Drosophila melanogaster [DefinedSet:R-CEL-2176487] p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] - Caenorhabditis elegans
maxDepth	3
modified	[InstanceEdit:9736949] Orlic-Milacic, Marija, 2021-07-15
name	p-T,2S-SMAD2,3:SMAD4
producedByEvent	[Reaction:R-HSA-2176475] Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-2176487

Referrals

(hasComponent)	[Complex:R-HSA-2176504] Ub-p-T-2S-SMAD2,3:SMAD4 [nucleoplasm] [Complex:R-HSA-2176495] p-T-2S-SMAD2,3:SMAD4:NEDDL4 [nucleoplasm] [Complex:R-HSA-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm]
(input)	[Reaction:R-HSA-2176491] NEDD4L binds phosphorylated linker region of SMAD2/3 [Reaction:R-HSA-2179274] SMURF2 binds SMAD3 phosphorylated in the linker region
(output)	[Reaction:R-HSA-2176475] Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9

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