Reactome | p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm]

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p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:2179275] ubiquitin-protein transferase activity of p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-2179276] SMURF2 monoubiquitinates SMAD3 - Homo sapiens
created	[InstanceEdit:2179278] Orlic-Milacic, M, 2012-04-03
dbId	2179277
displayName	p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm]
hasComponent	[DefinedSet:R-HSA-2176487] p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-178202] SMURF2 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Mus musculus [Complex:R-RNO-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Canis familiaris [Complex:R-BTA-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Bos taurus [Complex:R-SSC-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Sus scrofa [Complex:R-DRE-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Danio rerio [Complex:R-XTR-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Gallus gallus [Complex:R-DME-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Caenorhabditis elegans
isChimeric	false
maxDepth	4
modified	[InstanceEdit:9736955] Orlic-Milacic, Marija, 2021-07-15
name	p-T-2S-SMAD2,3:SMAD4:SMURF2
producedByEvent	[Reaction:R-HSA-2179274] SMURF2 binds SMAD3 phosphorylated in the linker region - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-2179277
updateTrackers	[UpdateTracker:9875109] Update Tracker - [Complex:2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - v44:[updateContainedComponent] [UpdateTracker:9902421] Update Tracker - [Complex:2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - v78:[modifyName, updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9875109] Update Tracker - [Complex:2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - v44:[updateContainedComponent] [UpdateTracker:9902421] Update Tracker - [Complex:2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - v78:[modifyName, updateContainedComponent]
(output)	[Reaction:R-HSA-2179274] SMURF2 binds SMAD3 phosphorylated in the linker region
(input)	[Reaction:R-HSA-2179276] SMURF2 monoubiquitinates SMAD3
(physicalEntity)	[CatalystActivity:2179275] ubiquitin-protein transferase activity of p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm]

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