Reactome | Caspase 3-mediated cleavage of PKC delta

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Caspase 3-mediated cleavage of PKC delta Show undefined attributes

authored	[InstanceEdit:201620] Schulze-Osthoff, K, 2007-09-03 07:52:18
catalystActivity	[CatalystActivity:114327] cysteine-type endopeptidase activity of Caspase-3 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:212535] Matthews, L, 2008-02-12 15:52:37
dbId	212552
displayName	Caspase 3-mediated cleavage of PKC delta
edited	[InstanceEdit:201589] Matthews, L, 2007-09-03 07:38:20
eventOf	[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-58200] PRKCD [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:212541] Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	Caspase 3-mediated cleavage of PKC delta
orthologousEvent	[Reaction:R-DME-212552] Caspase 3-mediated cleavage of PKC delta - Drosophila melanogaster [Reaction:R-GGA-212552] Caspase 3-mediated cleavage of PKC delta - Gallus gallus [Reaction:R-XTR-212552] Caspase 3-mediated cleavage of PKC delta - Xenopus tropicalis [Reaction:R-DRE-212552] Caspase 3-mediated cleavage of PKC delta - Danio rerio [Reaction:R-SSC-212552] Caspase 3-mediated cleavage of PKC delta - Sus scrofa [Reaction:R-BTA-212552] Caspase 3-mediated cleavage of PKC delta - Bos taurus [Reaction:R-CFA-212552] Caspase 3-mediated cleavage of PKC delta - Canis familiaris [Reaction:R-RNO-212552] Caspase 3-mediated cleavage of PKC delta - Rattus norvegicus [Reaction:R-MMU-212552] Caspase 3-mediated cleavage of PKC delta - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-212547] PRKCD(1-329) [cytosol] [EntityWithAccessionedSequence:R-HSA-212551] PRKCD(330-676) [cytosol]
precedingEvent	[Reaction:R-HSA-114252] Cleavage of Procaspase-3 by the apoptosome - Homo sapiens [Reaction:R-HSA-114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 - Homo sapiens [Reaction:R-HSA-418845] Activation of caspase-3 - Homo sapiens
releaseDate	2005-09-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:204051] Ranganathan, S, 2007-11-23 00:10:26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-212552
summation	[Summation:212543] Caspase mediated cleavage produces a constitutively active k...
updateTrackers	[UpdateTracker:9787671] Update Tracker - [Reaction:212552] Caspase 3-mediated cleavage of PKC delta - v44:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9787671] Update Tracker - [Reaction:212552] Caspase 3-mediated cleavage of PKC delta - v44:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-111465] Apoptotic cleavage of cellular proteins