Reactome | CYP2E1 reactions

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CYP2E1 reactions Show undefined attributes

authored	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:211969] Jassal, B, 2008-02-08 15:33:52
dbId	211999
displayName	CYP2E1 reactions
edited	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
eventOf	[Pathway:R-HSA-211981] Xenobiotics - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:8764] xenobiotic metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-76397] Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) - Homo sapiens [Reaction:R-HSA-76416] Benzene is hydroxylated to phenol - Homo sapiens [Reaction:R-HSA-76434] Dehalogenation of carbon tetrachloride to form a free radical - Homo sapiens [Reaction:R-HSA-76475] Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide - Homo sapiens [Reaction:R-HSA-143468] MEOS oxidizes ethanol to acetaldehyde - Homo sapiens [Reaction:R-HSA-76354] Vinyl chloride is oxidized to 2-Chloroethylene oxide - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2010-06-30
literatureReference	[LiteratureReference:211875] Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)--a review [LiteratureReference:211867] Oxidative stress, toxicology, and pharmacology of CYP2E1 [LiteratureReference:211884] Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1
maxDepth	2
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	CYP2E1 reactions
orthologousEvent	[Pathway:R-DDI-211999] CYP2E1 reactions - Dictyostelium discoideum [Pathway:R-CEL-211999] CYP2E1 reactions - Caenorhabditis elegans [Pathway:R-GGA-211999] CYP2E1 reactions - Gallus gallus [Pathway:R-XTR-211999] CYP2E1 reactions - Xenopus tropicalis [Pathway:R-DRE-211999] CYP2E1 reactions - Danio rerio [Pathway:R-SSC-211999] CYP2E1 reactions - Sus scrofa [Pathway:R-BTA-211999] CYP2E1 reactions - Bos taurus [Pathway:R-CFA-211999] CYP2E1 reactions - Canis familiaris [Pathway:R-RNO-211999] CYP2E1 reactions - Rattus norvegicus [Pathway:R-MMU-211999] CYP2E1 reactions - Mus musculus
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-211999
summation	[Summation:211862] CYP2E1 can metabolize and activate a large number of solvent...
updateTrackers	[UpdateTracker:9790344] Update Tracker - [Pathway:211999] CYP2E1 reactions - v33:[updateContainedRLE] [UpdateTracker:9791585] Update Tracker - [Pathway:211999] CYP2E1 reactions - v28:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9790344] Update Tracker - [Pathway:211999] CYP2E1 reactions - v33:[updateContainedRLE] [UpdateTracker:9791585] Update Tracker - [Pathway:211999] CYP2E1 reactions - v28:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-211981] Xenobiotics

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