Reactome | CYP2E1 reactions

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CYP2E1 reactions Show undefined attributes

compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222315
displayName	CYP2E1 reactions
eventOf	[Pathway:R-RNO-211981] Xenobiotics - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:8764] xenobiotic metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-76397] Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) - Rattus norvegicus [Reaction:R-RNO-76416] Benzene is hydroxylated to phenol - Rattus norvegicus [Reaction:R-RNO-76434] Dehalogenation of carbon tetrachloride to form a free radical - Rattus norvegicus [Reaction:R-RNO-76475] Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide - Rattus norvegicus [Reaction:R-RNO-143468] MEOS oxidizes ethanol to acetaldehyde - Rattus norvegicus [Reaction:R-RNO-76354] Vinyl chloride is oxidized to 2-Chloroethylene oxide - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-211999] CYP2E1 reactions - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	CYP2E1 reactions
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-211999
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-211981] Xenobiotics
(inferredTo)	[Pathway:R-HSA-211999] CYP2E1 reactions