Reactome | Trans-phosphorylation of Tie2

Schema > Reaction > Entries

Trans-phosphorylation of Tie2 Show undefined attributes

authored	[InstanceEdit:215562] Garapati, P V, de Bono, B, 2008-03-05 10:26:56
catalystActivity	[CatalystActivity:210866] protein tyrosine kinase activity of ANGPT1:TEK [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:210879] Garapati, P V, 2008-01-17 14:13:36
dbId	210872
displayName	Trans-phosphorylation of Tie2
eventOf	[Pathway:R-HSA-210993] Tie2 Signaling - Homo sapiens
followingEvent	[Reaction:R-HSA-204813] Interaction of Tie2 and Grb14 - Homo sapiens [Reaction:R-HSA-204873] Interaction of Tie2 and Shp2 - Homo sapiens [Reaction:R-HSA-204773] Interaction of Tie2 and Grb7 - Homo sapiens [Reaction:R-HSA-204850] Interaction of Tie2 and Dok-2 - Homo sapiens [Reaction:R-HSA-204861] Interaction of Tie2 and Shc1 - Homo sapiens [Reaction:R-HSA-204798] Interaction of Tie2 and p85 of PI3K - Homo sapiens [Reaction:R-HSA-204871] Interaction of Tie2 and Grb2 - Homo sapiens
inferredFrom	[Reaction:R-MMU-211119] Trans-phosphorylation of Tie2 - Mus musculus
input	[Complex:R-HSA-210862] 2xANGPT1:TEK [plasma membrane] 12 × [SimpleEntity:R-ALL-113592] ATP [cytosol]
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:210857] Functional significance of Tie2 signaling in the adult vasculature
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Trans-phosphorylation of Tie2
output	12 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-210859] Phosphorylated Tie2 in Tie2/Akt dimer [plasma membrane]
precedingEvent	[Reaction:R-HSA-210881] Dimerization of Tie2/Ang1 complex - Homo sapiens
releaseDate	2008-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-210872
summation	[Summation:210876] The dimerization of Tie2 leads to autophosphorylation and ac...

Referrals

(hasEvent)	[Pathway:R-HSA-210993] Tie2 Signaling
(precedingEvent)	[Reaction:R-HSA-204813] Interaction of Tie2 and Grb14 [Reaction:R-HSA-204873] Interaction of Tie2 and Shp2 [Reaction:R-HSA-204773] Interaction of Tie2 and Grb7 [Reaction:R-HSA-204850] Interaction of Tie2 and Dok-2 [Reaction:R-HSA-204861] Interaction of Tie2 and Shc1 [Reaction:R-HSA-204798] Interaction of Tie2 and p85 of PI3K [Reaction:R-HSA-204871] Interaction of Tie2 and Grb2
(inferredTo)	[Reaction:R-MMU-211119] Trans-phosphorylation of Tie2