Reactome | Trans-phosphorylation of Tie2

Schema > Reaction > Entries

authored	[InstanceEdit:215562] Garapati, P V, de Bono, B, 2008-03-05 10:26:56
catalystActivity	[CatalystActivity:211124] protein tyrosine kinase activity of Tie2/Ang1 dimer [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:211109] Garapati, P V, 2008-01-28 10:30:53
dbId	211119
displayName	Trans-phosphorylation of Tie2
edited	[InstanceEdit:349793] Garapati, P V, 2008-05-13 11:04:33
input	10 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-MMU-211106] Tie2/Ang1 dimer [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:210857] Functional significance of Tie2 signaling in the adult vasculature
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Trans-phosphorylation of Tie2
orthologousEvent	[Reaction:R-HSA-210872] Trans-phosphorylation of Tie2 - Homo sapiens
output	10 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-MMU-211103] Phosphorylated Tie2 in Tie2/Ang1 dimer [plasma membrane]
releaseDate	2008-03-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-211119
summation	[Summation:210876] The dimerization of Tie2 leads to autophosphorylation and ac...

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