Reactome | Tie2 Signaling

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Tie2 Signaling Show undefined attributes

authored	[InstanceEdit:215562] Garapati, P V, de Bono, B, 2008-03-05 10:26:56
created	[InstanceEdit:210989] Garapati, P V, 2008-01-22 15:06:28
dbId	210993
displayName	Tie2 Signaling
eventOf	[Pathway:R-HSA-202733] Cell surface interactions at the vascular wall - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-204779] Interaction of Tie2 with Ang1 - Homo sapiens [Reaction:R-HSA-210881] Dimerization of Tie2/Ang1 complex - Homo sapiens [Reaction:R-HSA-210872] Trans-phosphorylation of Tie2 - Homo sapiens [Reaction:R-HSA-204798] Interaction of Tie2 and p85 of PI3K - Homo sapiens [Reaction:R-HSA-204871] Interaction of Tie2 and Grb2 - Homo sapiens [Reaction:R-HSA-210974] Interaction of SOS-1 to Tie2 bound Grb2 - Homo sapiens [Reaction:R-HSA-210977] Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) - Homo sapiens [Reaction:R-HSA-204861] Interaction of Tie2 and Shc1 - Homo sapiens [Reaction:R-HSA-204850] Interaction of Tie2 and Dok-2 - Homo sapiens [Reaction:R-HSA-204863] Interaction of Tie2 with Ang2 - Homo sapiens [Reaction:R-HSA-204824] Interaction of Tie2 and Ang4 - Homo sapiens [Reaction:R-HSA-204873] Interaction of Tie2 and Shp2 - Homo sapiens [Reaction:R-HSA-204773] Interaction of Tie2 and Grb7 - Homo sapiens [Reaction:R-HSA-204813] Interaction of Tie2 and Grb14 - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:210882] Angiopoietin and Tie signaling pathways in vascular development [LiteratureReference:204811] Tek/Tie2 signaling: new and old partners [LiteratureReference:204852] The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R [LiteratureReference:204866] The angiopoietins and Tie2/Tek: adding to the complexity of cardiovascular development
modified	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
name	Tie2 Signaling
orthologousEvent	[Pathway:R-CFA-210993] Tie2 Signaling - Canis familiaris [Pathway:R-GGA-210993] Tie2 Signaling - Gallus gallus [Pathway:R-XTR-210993] Tie2 Signaling - Xenopus tropicalis [Pathway:R-DRE-210993] Tie2 Signaling - Danio rerio [Pathway:R-SSC-210993] Tie2 Signaling - Sus scrofa [Pathway:R-BTA-210993] Tie2 Signaling - Bos taurus [Pathway:R-RNO-210993] Tie2 Signaling - Rattus norvegicus [Pathway:R-MMU-210993] Tie2 Signaling - Mus musculus
releaseDate	2008-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-210993
summation	[Summation:211545] The Tie2/Tek receptor tyrosine kinase plays a pivotal role i...

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[Pathway:R-HSA-202733] Cell surface interactions at the vascular wall

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