Reactome | Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane

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Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane Show undefined attributes

authored	[InstanceEdit:201063] Gopinathrao, G, 2007-07-29 21:03:03
catalystActivity	[CatalystActivity:200567] carnitine:O-acyl-L-carnitine antiporter activity of SLC25A20 [mitochondrial inner membrane]
catalystActivityReference	[CatalystActivityReference:9643149] carnitine:acyl carnitine antiporter activity of SLC25A20 [mitochondrial inner membrane] Cloning of the human carnitine-acylcarnitine carrier cDNA and identification of the molecular defect in a patient
category	transition
compartment	[Compartment:17927] mitochondrial intermembrane space [Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:200415] Gopinathrao, G, 2007-07-18 19:50:24
crossReference	[DatabaseIdentifier:12667834] RHEA:49916 [DatabaseIdentifier:9971093] RHEA:49926
dbId	200424
displayName	Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane
eventOf	[Pathway:R-HSA-200425] Carnitine shuttle - Homo sapiens
followingEvent	[Reaction:R-HSA-200410] CPT2 converts acylcarnitine to acyl-CoA - Homo sapiens
input	[DefinedSet:R-ALL-9971099] Acyl-CAR [mitochondrial intermembrane space] [SimpleEntity:R-ALL-201023] CAR [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:201067] Cloning of the human carnitine-acylcarnitine carrier cDNA and identification of the molecular defect in a patient
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane (R)-carnitine(in) + O-acyl-(R)-carnitine(out) = (R)-carnitine(out) + O-acyl-(R)-carnitine(in)
orthologousEvent	[Reaction:R-CFA-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Canis familiaris [Reaction:R-SCE-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Saccharomyces cerevisiae [Reaction:R-CEL-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Caenorhabditis elegans [Reaction:R-DME-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Drosophila melanogaster [Reaction:R-GGA-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Gallus gallus [Reaction:R-XTR-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Xenopus tropicalis [Reaction:R-DRE-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Danio rerio [Reaction:R-SSC-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Sus scrofa [Reaction:R-BTA-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Bos taurus [Reaction:R-RNO-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Rattus norvegicus [Reaction:R-MMU-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Mus musculus
output	[DefinedSet:R-ALL-9971097] Acyl-CAR [mitochondrial matrix] [SimpleEntity:R-ALL-549207] CAR [mitochondrial intermembrane space]
precedingEvent	[Reaction:R-HSA-200406] CPT1A transfers PALM to CAR - Homo sapiens [Reaction:R-HSA-9911362] CPT1B transfers PALM to CAR - Homo sapiens
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2007-09-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:201322] D'Eustachio, P, 2007-07-31 18:50:15 [InstanceEdit:9971588] D'Eustachio, Peter, 2025-11-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-200424
summation	[Summation:201025] The carnitine-acylcarnitine transporter (SLC25A20 / CACT), e...
updateTrackers	[UpdateTracker:9790394] Update Tracker - [Reaction:200424] Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane - v33:[add_removeOutput, modifyText] [UpdateTracker:9971793] Update Tracker - [Reaction:200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - v95:[add_removeInput, add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9790394] Update Tracker - [Reaction:200424] Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane - v33:[add_removeOutput, modifyText] [UpdateTracker:9971793] Update Tracker - [Reaction:200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - v95:[add_removeInput, add_removeOutput]
(hasEvent)	[Pathway:R-HSA-200425] Carnitine shuttle
(precedingEvent)	[Reaction:R-HSA-200410] CPT2 converts acylcarnitine to acyl-CoA

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