Reactome | Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane

Schema > Reaction > Entries

Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane Show undefined attributes

catalystActivity	[CatalystActivity:10351511] carnitine:O-acyl-L-carnitine antiporter activity of SLC25A20 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:17927] mitochondrial intermembrane space [Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10351513
displayName	Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane
eventOf	[Pathway:R-BTA-200425] Carnitine shuttle - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-200410] CPT2 converts acylcarnitine to acyl-CoA - Bos taurus
inferredFrom	[Reaction:R-HSA-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane - Homo sapiens
input	[DefinedSet:R-ALL-9971099] Acyl-CAR [mitochondrial intermembrane space] [SimpleEntity:R-ALL-201023] CAR [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane (R)-carnitine(in) + O-acyl-(R)-carnitine(out) = (R)-carnitine(out) + O-acyl-(R)-carnitine(in)
output	[DefinedSet:R-ALL-9971097] Acyl-CAR [mitochondrial matrix] [SimpleEntity:R-ALL-549207] CAR [mitochondrial intermembrane space]
precedingEvent	[Reaction:R-BTA-200406] CPT1A transfers PALM to CAR - Bos taurus [Reaction:R-BTA-9911362] CPT1B transfers PALM to CAR - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-200424
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-200425] Carnitine shuttle
(precedingEvent)	[Reaction:R-BTA-200410] CPT2 converts acylcarnitine to acyl-CoA
(inferredTo)	[Reaction:R-HSA-200424] Exchange of acylcarnitine and carnitine across the inner mitochondrial membrane

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