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Entries
PPARA activates gene expression
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authored
[InstanceEdit:1989769] May, B, 2011-11-08
compartment
[Compartment:70101] cytosol
[Compartment:12045] endoplasmic reticulum membrane
[Compartment:984] extracellular region
[Compartment:13977] lipid droplet
[Compartment:70616] mitochondrial inner membrane
[Compartment:5460] mitochondrial matrix
[Compartment:17906] mitochondrial outer membrane
[Compartment:7660] nucleoplasm
[Compartment:17951] peroxisomal matrix
[Compartment:17947] peroxisomal membrane
[Compartment:876] plasma membrane
created
[InstanceEdit:1989780] May, B, 2011-11-13
dbId
1989781
displayName
PPARA activates gene expression
edited
[InstanceEdit:1989769] May, B, 2011-11-08
eventOf
[Pathway:R-HSA-400206] Regulation of lipid metabolism by PPARalpha - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:3320] regulation of metabolic process
hasDiagram
false
hasEHLD
false
hasEvent
[BlackBoxEvent:R-HSA-1655826] Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) - Homo sapiens
[BlackBoxEvent:R-HSA-1989765] Expression of ABCA1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989762] Expression of ABCB4 - Homo sapiens
[BlackBoxEvent:R-HSA-1989745] Expression of ACADM - Homo sapiens
[BlackBoxEvent:R-HSA-1989749] Expression of ACOX1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989778] Expression of ACSL1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989774] Expression of AGT - Homo sapiens
[BlackBoxEvent:R-HSA-1592238] Expression of ALAS1 - Homo sapiens
[BlackBoxEvent:R-HSA-560473] Expression of ANGPTL4 - Homo sapiens
[BlackBoxEvent:R-HSA-1989779] Expression of ANKRD1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989754] Expression of APOA1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989776] Expression of APOA2 - Homo sapiens
[BlackBoxEvent:R-HSA-1989761] Expression of APOA5 - Homo sapiens
[BlackBoxEvent:R-HSA-560517] Expression of CD36 (platelet glycoprotein IV, FAT) - Homo sapiens
[BlackBoxEvent:R-HSA-1801587] Expression of CPT1A - Homo sapiens
[BlackBoxEvent:R-HSA-1989773] Expression of CPT2 - Homo sapiens
[BlackBoxEvent:R-HSA-1989764] Expression of CYP1A1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989755] Expression of CYP4A11 - Homo sapiens
[BlackBoxEvent:R-HSA-1989746] Expression of CYP7A1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989751] Expression of FABP1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989757] Expression of FADS1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989750] Expression of FATP1 (SLC27A1) - Homo sapiens
[BlackBoxEvent:R-HSA-1989747] Expression of FHL2 - Homo sapiens
[BlackBoxEvent:R-HSA-1655850] Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) - Homo sapiens
[BlackBoxEvent:R-HSA-1989759] Expression of G0S2 - Homo sapiens
[BlackBoxEvent:R-HSA-1989772] Expression of GLIPR1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989748] Expression of GRHL1 - Homo sapiens
[BlackBoxEvent:R-HSA-1655848] Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) - Homo sapiens
[BlackBoxEvent:R-HSA-1989760] Expression of HMGCS2 - Homo sapiens
[BlackBoxEvent:R-HSA-1989756] Expression of ME1 - Homo sapiens
[BlackBoxEvent:R-HSA-1368065] Expression of NPAS2 - Homo sapiens
[BlackBoxEvent:R-HSA-1989753] Expression of PEX11A - Homo sapiens
[BlackBoxEvent:R-HSA-1989770] Expression of PLIN2 - Homo sapiens
[BlackBoxEvent:R-HSA-879724] Expression of PPARA - Homo sapiens
[BlackBoxEvent:R-HSA-1989777] Expression of RGL1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989775] Expression of SULT2A1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989768] Expression of TIAM2 - Homo sapiens
[BlackBoxEvent:R-HSA-1989771] Expression of TNFRSF21 - Homo sapiens
[BlackBoxEvent:R-HSA-1989767] Expression of TRIB3 - Homo sapiens
[BlackBoxEvent:R-HSA-1989752] Expression of TXNRD1 - Homo sapiens
[BlackBoxEvent:R-HSA-1989758] Expression of UGT1A9 - Homo sapiens
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:400147] Peroxisome proliferator activated receptors and lipoprotein metabolism
[LiteratureReference:400170] Peroxisome proliferator-activated receptor alpha target genes
[LiteratureReference:400211] Peroxisome proliferator-activated receptors, coactivators, and downstream targets
[LiteratureReference:400127] Peroxisome proliferator-activated receptors: nuclear control of metabolism
[LiteratureReference:1998761] Peroxisome proliferator-activated receptor alpha target genes
modified
[InstanceEdit:9847082] Weiser, Joel, 2023-10-12
name
PPARA activates gene expression
releaseDate
2011-12-06
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:425906] Kersten, S, 2009-06-08
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-1989781
summation
[Summation:400179] The set of genes regulated by PPAR-alpha is not fully known ...
Referrals
(hasEvent)
[Pathway:R-HSA-400206] Regulation of lipid metabolism by PPARalpha
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