Reactome | Expression of CYP1A1

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Expression of CYP1A1 Show undefined attributes

authored	[InstanceEdit:1989769] May, B, 2011-11-08
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:1989763] May, B, 2011-11-13
dbId	1989764
displayName	Expression of CYP1A1
edited	[InstanceEdit:1989769] May, B, 2011-11-08
eventOf	[Pathway:R-HSA-1989781] PPARA activates gene expression - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:17788] positive regulation of transcription by RNA polymerase II
input	[EntityWithAccessionedSequence:R-HSA-5649956] CYP1A1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:561142] Profiling of promoter occupancy by PPAR{alpha} in human hepatoma cells via ChIP-chip analysis [LiteratureReference:561153] Comparative analysis of gene regulation by the transcription factor PPARalpha between mouse and human [LiteratureReference:8937160] Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor [LiteratureReference:8937206] The aryl hydrocarbon receptor complex and the control of gene expression [LiteratureReference:8937186] The arylhydrocarbon receptor repressor (AhRR): structure, expression, and function
maxDepth	1
modified	[InstanceEdit:9961204] D'Eustachio, Peter, 2025-07-21
name	Expression of CYP1A1
output	[EntityWithAccessionedSequence:R-HSA-52623] CYP1A1 [endoplasmic reticulum membrane]
precedingEvent	[BlackBoxEvent:R-HSA-400143] Fatty acid ligands activate PPARA - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-1989817] Positive gene expression regulation by 'PPARA:RXRA Coactivator complex [nucleoplasm]' [NegativeGeneExpressionRegulation:R-HSA-8937237] Negative gene expression regulation by 'AHRR:ARNT [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-8937241] Positive gene expression regulation by 'AHR:TCDD:ARNT [nucleoplasm]'
regulationReference	[RegulationReference:9642535] Positive gene expression regulation by 'PPARA:RXRA Coactivator complex [nucleoplasm]' Profiling of promoter occupancy by PPAR{alpha} in human hepatoma cells via ChIP-chip analysis
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:425906] Kersten, S, 2009-06-08
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-1989764
summation	[Summation:1989636] The CYP1A1 gene is transcribed to yield mRNA and the mRNA is...
updateTrackers	[UpdateTracker:9782336] Update Tracker - [BlackBoxEvent:1989764] Expression of CYP1A1 - v59:[addLiteratureReference, addRegulator, modifyText] [UpdateTracker:9785316] Update Tracker - [BlackBoxEvent:1989764] Expression of CYP1A1 - v52:[addInput]

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(updatedInstance)	[UpdateTracker:9782336] Update Tracker - [BlackBoxEvent:1989764] Expression of CYP1A1 - v59:[addLiteratureReference, addRegulator, modifyText] [UpdateTracker:9785316] Update Tracker - [BlackBoxEvent:1989764] Expression of CYP1A1 - v52:[addInput]
(hasEvent)	[Pathway:R-HSA-1989781] PPARA activates gene expression

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