Reactome | Activated overexpressed FGFR1 homodimers [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1982040] Rothfels, K, 2011-11-09
crossReference	[DatabaseIdentifier:12020755] Mondo:0008903
dbId	1982041
disease	[Disease:1500689] cancer [Disease:1500699] lung cancer [Disease:1981182] lung squamous cell carcinoma
displayName	Activated overexpressed FGFR1 homodimers [plasma membrane]
hasMember	[Complex:R-HSA-1982038] Activated overexpressed FGFR1b homodimer [plasma membrane] - Homo sapiens [Complex:R-HSA-1982036] Activated overexpressed FGFR1c homodimer [plasma membrane] - Homo sapiens
inDisease	true
literatureReference	[LiteratureReference:1982030] Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer [LiteratureReference:1982028] Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer
maxDepth	3
memberOf	[DefinedSet:R-HSA-5655215] Activated FGFR1 mutants [plasma membrane] - Homo sapiens
name	Activated overexpressed FGFR1 homodimers
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-1982041
updateTrackers	[UpdateTracker:9890268] Update Tracker - [DefinedSet:1982041] Activated overexpressed FGFR1 homodimers [plasma membrane] - v52:[updateContainedMemberOrCandidate] [UpdateTracker:9897123] Update Tracker - [DefinedSet:1982041] Activated overexpressed FGFR1 homodimers [plasma membrane] - v61:[updateContainedMemberOrCandidate]

(updatedInstance)	[UpdateTracker:9890268] Update Tracker - [DefinedSet:1982041] Activated overexpressed FGFR1 homodimers [plasma membrane] - v52:[updateContainedMemberOrCandidate] [UpdateTracker:9897123] Update Tracker - [DefinedSet:1982041] Activated overexpressed FGFR1 homodimers [plasma membrane] - v61:[updateContainedMemberOrCandidate]
(hasMember)	[DefinedSet:R-HSA-5655215] Activated FGFR1 mutants [plasma membrane]