Reactome | TNPO1 [cytosol]

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TNPO1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-NUL-9616163] TNPO1:nup107-160 complex [cytosol] - Homo sapiens [Complex:R-HSA-5624928] KIF17 dimer:TNPO1 [cytosol] - Homo sapiens [Complex:R-HSA-450365] TTP:mRNA Complex [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-NUL-9615968] Transportin sequesters the Nup107-160 complex - Homo sapiens [Reaction:R-HSA-5624951] TNPO1 binds KIF17 dimer - Homo sapiens [Reaction:R-HSA-450400] ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs - Homo sapiens
created	[InstanceEdit:180750] Matthews, L, 2006-06-02 10:45:32
dbId	180743
displayName	TNPO1 [cytosol]
endCoordinate	898
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-180743] Tnpo1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-180743] Tnpo1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-BTA-180743] TNPO1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-180743] TNPO1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-180743] tnpo1 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-180743] tnpo1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-DME-180743] Tnpo [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-180743] imb-2 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-180743] tnpo [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SCE-180743] KAP104 [cytosol] - Saccharomyces cerevisiae
maxDepth	1
memberOf	[DefinedSet:R-HSA-9615955] KPNB1,TNPO1 [cytosol] - Homo sapiens
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	TNPO1 Importin beta-2 Transportin-1
referenceEntity	[ReferenceGeneProduct:uniprot:Q92973] UniProt:Q92973 TNPO1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-180743
startCoordinate	1
updateTrackers	[UpdateTracker:9882226] Update Tracker - [EntityWithAccessionedSequence:180743] TNPO1 [cytosol] - v45:[addName] [UpdateTracker:9879479] Update Tracker - [EntityWithAccessionedSequence:180743] TNPO1 [cytosol] - v44:[modifyEndCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9882226] Update Tracker - [EntityWithAccessionedSequence:180743] TNPO1 [cytosol] - v45:[addName] [UpdateTracker:9879479] Update Tracker - [EntityWithAccessionedSequence:180743] TNPO1 [cytosol] - v44:[modifyEndCoordinate]
(input)	[Reaction:R-HSA-5624951] TNPO1 binds KIF17 dimer [Reaction:R-HSA-450400] ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs [Reaction:R-NUL-9615968] Transportin sequesters the Nup107-160 complex
(hasComponent)	[Complex:R-HSA-5624928] KIF17 dimer:TNPO1 [cytosol] [Complex:R-HSA-450541] Phosphorylated TTP:mRNA Complex [cytosol] [Complex:R-HSA-450365] TTP:mRNA Complex [cytosol] [Complex:R-HSA-9616199] RAN:GTP:TNPO1 [cytosol] [Complex:R-NUL-9616163] TNPO1:nup107-160 complex [cytosol]
(hasMember)	[DefinedSet:R-HSA-9615955] KPNB1,TNPO1 [cytosol]

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