Reactome | Phosphorylated TTP:mRNA Complex [cytosol]

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Phosphorylated TTP:mRNA Complex [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-450420] Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-450394] p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta - Homo sapiens
created	[InstanceEdit:450588] May, B, 2009-12-16
dbId	450541
displayName	Phosphorylated TTP:mRNA Complex [cytosol]
hasComponent	[OtherEntity:R-ALL-450597] mRNA Transcript Targeted by Tristetraproline [cytosol] [EntityWithAccessionedSequence:R-HSA-450496] p-S60,S186-ZFP36 [cytosol] [EntityWithAccessionedSequence:R-HSA-180743] TNPO1 [cytosol]
inDisease	false
inferredTo	[Complex:R-MMU-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Mus musculus [Complex:R-RNO-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Rattus norvegicus [Complex:R-BTA-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Bos taurus [Complex:R-SSC-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Sus scrofa [Complex:R-DRE-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Danio rerio [Complex:R-XTR-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Xenopus tropicalis [Complex:R-DME-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Drosophila melanogaster [Complex:R-CEL-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Caenorhabditis elegans [Complex:R-DDI-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Dictyostelium discoideum [Complex:R-SCE-450541] Phosphorylated TTP:mRNA Complex [cytosol] - Saccharomyces cerevisiae
isChimeric	false
literatureReference	[LiteratureReference:450586] Control of mRNA decay by phosphorylation of tristetraprolin
maxDepth	2
modified	[InstanceEdit:451138] May, B, 2009-12-30
name	Phosphorylated TTP:mRNA Complex
producedByEvent	[Reaction:R-HSA-450463] MK2 phosphorylates ZFP36 (Tristetraproline, TTP) - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-450541

Referrals

(hasComponent)	[Complex:R-HSA-450420] Phosphorylated TTP:mRNA:14-3-3 Complex [cytosol]
(input)	[Reaction:R-HSA-450394] p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta
(output)	[Reaction:R-HSA-450463] MK2 phosphorylates ZFP36 (Tristetraproline, TTP)

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