Reactome | Dimerized phospho-IRF3/IRF7 is transported to the nucleus

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Dimerized phospho-IRF3/IRF7 is transported to the nucleus Show undefined attributes

authored	[InstanceEdit:450323] Shamovsky, V, 2009-12-16
category	transition
compartment	[Compartment:70101] cytosol [Compartment:13231] nuclear envelope [Compartment:7660] nucleoplasm
created	[InstanceEdit:177664] Gillespie, ME, 2006-04-03 21:05:10
dbId	177671
displayName	Dimerized phospho-IRF3/IRF7 is transported to the nucleus
edited	[InstanceEdit:1485578] Shamovsky, V, 2011-08-12
eventOf	[Pathway:R-HSA-9013973] TICAM1-dependent activation of IRF3/IRF7 - Homo sapiens
input	[DefinedSet:R-HSA-450256] phosphorylated IRF3 and/or IRF7 dimer [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:166859] IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Dimerized phospho-IRF3/IRF7 is transported to the nucleus
orthologousEvent	[Reaction:R-GGA-433967] Dimerized Phospho-IRF3 is Transported To The Nucleus - Gallus gallus [Reaction:R-GGA-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Gallus gallus [Reaction:R-XTR-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Xenopus tropicalis [Reaction:R-DRE-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Danio rerio [Reaction:R-SSC-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Sus scrofa [Reaction:R-BTA-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Bos taurus [Reaction:R-CFA-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Canis familiaris [Reaction:R-RNO-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Rattus norvegicus [Reaction:R-MMU-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Mus musculus
output	[DefinedSet:R-HSA-450349] phosphorylated IRF3 and/or IRF7 dimer [nucleoplasm]
precedingEvent	[Reaction:R-HSA-168933] Dimerization of phosphorylated IRF3/IRF7 - Homo sapiens
releaseDate	2010-12-14
requiredInputComponent	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope] - Homo sapiens
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188961] Gay, NJ, 2006-04-24 16:48:17 [InstanceEdit:1095192] Gillespie, ME, 2010-11-30 [InstanceEdit:2582977] Fitzgerald, Katherine A, 2012-11-13
revised	[InstanceEdit:442879] Shamovsky, V, 2009-09-29
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-177671
summation	[Summation:178674] IRF3-P:IRF3-P' is translocated from cytosol to nucleoplasm.
updateTrackers	[UpdateTracker:9790049] Update Tracker - [Reaction:177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - v35:[modifyText] [UpdateTracker:9790940] Update Tracker - [Reaction:177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - v32:[add_removeInput, add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9790049] Update Tracker - [Reaction:177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - v35:[modifyText] [UpdateTracker:9790940] Update Tracker - [Reaction:177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - v32:[add_removeInput, add_removeOutput]
(hasEvent)	[Pathway:R-HSA-9013973] TICAM1-dependent activation of IRF3/IRF7 [Pathway:R-HSA-936964] Activation of IRF3, IRF7 mediated by TBK1, IKK? (IKBKE)