Reactome | Dimerized Phospho-IRF3 is Transported To The Nucleus

Schema > Reaction > Entries

authored	[InstanceEdit:434153] Shamovsky, V, 2009-08-26
category	transition
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm [Compartment:13231] nuclear envelope
created	[InstanceEdit:434122] Shamovsky, V, 2009-08-26
dbId	433967
displayName	Dimerized Phospho-IRF3 is Transported To The Nucleus
edited	[InstanceEdit:668815] Shamovsky, V, 2010-05-04
eventOf	[Pathway:R-GGA-434136] Viral dsRNA:TLR3:TICAM1 Complex Activates TBK1 - Gallus gallus [Pathway:R-GGA-1227882] TRAF mediated activation of IRF - Gallus gallus
inferredFrom	[Reaction:R-HSA-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus - Homo sapiens
input	[Complex:R-GGA-433903] Phosphorylated IRF3 : IRF3 dimer [cytosol]
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:166859] IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Dimerized Phospho-IRF3 is Transported To The Nucleus
output	[Complex:R-GGA-434029] Phosphorylated IRF3 : IRF3 [nucleoplasm]
precedingEvent	[Reaction:R-GGA-434027] Dimerization of Phospho-IRF3 - Gallus gallus
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:789693] D'Eustachio, P, 2010-05-23
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-433967
summation	[Summation:813672] Phosphorylation and dimerization of IRF3 results in the cyto...

(hasEvent)	[Pathway:R-GGA-1227882] TRAF mediated activation of IRF [Pathway:R-GGA-434136] Viral dsRNA:TLR3:TICAM1 Complex Activates TBK1 [Pathway:R-GGA-433819] Viral dsRNA:TLR3:TICAM1 Complex Activates IKBKE_CHICK
(inferredTo)	[Reaction:R-HSA-177671] Dimerized phospho-IRF3/IRF7 is transported to the nucleus

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