Reactome | Glutathione synthesis and recycling

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Glutathione synthesis and recycling Show undefined attributes

authored	[InstanceEdit:156610] Jassal, B, 2004-11-30 16:21:24
created	[InstanceEdit:174378] Jassal, Bijay, 2006-02-17
dbId	174403
displayName	Glutathione synthesis and recycling
edited	[InstanceEdit:350358] Jassal, Bijay, 2008-05-19
eventOf	[Pathway:R-HSA-156590] Glutathione conjugation - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:21535] glutathione biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-1247935] OPLAH hydrolyses OPRO to L-Glu - Homo sapiens [Reaction:R-HSA-174367] GCL ligates L-Glu to L-Cys - Homo sapiens [Reaction:R-HSA-1247922] GGCT transforms gGluCys to OPRO - Homo sapiens [Reaction:R-HSA-174394] GSS:Mg2+ dimer synthesizes GSH - Homo sapiens [BlackBoxEvent:R-HSA-1247915] GSH translocates from cytosol to extracellular region - Homo sapiens [Reaction:R-HSA-8943279] GGT dimers hydrolyse GSH - Homo sapiens [BlackBoxEvent:R-HSA-1247939] CysGly translocates from extracellular region to cytosol - Homo sapiens [Reaction:R-HSA-1247910] CNDP2:2Mn2+ dimer hydrolyses CysGly - Homo sapiens [Reaction:R-HSA-6785928] CHAC1,2 cleaves GSH to OPRO and CysGly - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1295473] Glutathione metabolism and its selective modification
modified	[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name	Glutathione synthesis and recycling
orthologousEvent	[Pathway:R-PFA-174403] Glutathione synthesis and recycling - Plasmodium falciparum [Pathway:R-SCE-174403] Glutathione synthesis and recycling - Saccharomyces cerevisiae [Pathway:R-SPO-174403] Glutathione synthesis and recycling - Schizosaccharomyces pombe [Pathway:R-DDI-174403] Glutathione synthesis and recycling - Dictyostelium discoideum [Pathway:R-CEL-174403] Glutathione synthesis and recycling - Caenorhabditis elegans [Pathway:R-DME-174403] Glutathione synthesis and recycling - Drosophila melanogaster [Pathway:R-GGA-174403] Glutathione synthesis and recycling - Gallus gallus [Pathway:R-XTR-174403] Glutathione synthesis and recycling - Xenopus tropicalis [Pathway:R-DRE-174403] Glutathione synthesis and recycling - Danio rerio [Pathway:R-SSC-174403] Glutathione synthesis and recycling - Sus scrofa [Pathway:R-BTA-174403] Glutathione synthesis and recycling - Bos taurus [Pathway:R-CFA-174403] Glutathione synthesis and recycling - Canis familiaris [Pathway:R-RNO-174403] Glutathione synthesis and recycling - Rattus norvegicus [Pathway:R-MMU-174403] Glutathione synthesis and recycling - Mus musculus
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1299489] D'Eustachio, P, 2011-05-23
revised	[InstanceEdit:1299386] Jassal, B, 2011-05-23 [InstanceEdit:5602271] Jassal, Bijay, 2014-06-23
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-174403
summation	[Summation:211753] The combination of glutamate, cysteine and ATP is required t...

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[Pathway:R-HSA-156590] Glutathione conjugation

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