Reactome | Adenylate cyclase converts ATP into cyclic AMP

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Adenylate cyclase converts ATP into cyclic AMP Show undefined attributes

authored	[InstanceEdit:112007] Le Novere, N, Jassal, B, 2004-03-31 12:22:05
catalystActivity	[CatalystActivity:170668] adenylate cyclase activity of G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:170673] Jassal, B, 2006-01-10 11:11:27
crossReference	[DatabaseIdentifier:12667476] RHEA:15390
dbId	170676
displayName	Adenylate cyclase converts ATP into cyclic AMP
edited	[InstanceEdit:379927] Jassal, Bijay, 2008-11-06
eventOf	[Pathway:R-HSA-170660] Adenylate cyclase activating pathway - Homo sapiens
followingEvent	[Reaction:R-HSA-170685] Adenylaye cyclase increases the GTPase activity of G alpha-olf - Homo sapiens [Reaction:R-HSA-111962] PDE4A,C,D hydrolyse cAMP - Homo sapiens [Reaction:R-HSA-9644869] p-S54-PDE4B hydrolyses cAMP - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:374961] Purification and characterization of a soluble form of mammalian adenylyl cyclase
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	Adenylate cyclase converts ATP into cyclic AMP
orthologousEvent	[Reaction:R-DDI-170676] Adenylate cyclase converts ATP into cyclic AMP - Dictyostelium discoideum [Reaction:R-CEL-170676] Adenylate cyclase converts ATP into cyclic AMP - Caenorhabditis elegans [Reaction:R-DME-170676] Adenylate cyclase converts ATP into cyclic AMP - Drosophila melanogaster [Reaction:R-GGA-170676] Adenylate cyclase converts ATP into cyclic AMP - Gallus gallus [Reaction:R-XTR-170676] Adenylate cyclase converts ATP into cyclic AMP - Xenopus tropicalis [Reaction:R-DRE-170676] Adenylate cyclase converts ATP into cyclic AMP - Danio rerio [Reaction:R-SSC-170676] Adenylate cyclase converts ATP into cyclic AMP - Sus scrofa [Reaction:R-BTA-170676] Adenylate cyclase converts ATP into cyclic AMP - Bos taurus [Reaction:R-CFA-170676] Adenylate cyclase converts ATP into cyclic AMP - Canis familiaris [Reaction:R-RNO-170676] Adenylate cyclase converts ATP into cyclic AMP - Rattus norvegicus [Reaction:R-MMU-170676] Adenylate cyclase converts ATP into cyclic AMP - Mus musculus
output	[SimpleEntity:R-ALL-30389] cAMP [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent	[Reaction:R-HSA-170672] Galpha-olf:GTP binds to adenylate cyclase and activates it - Homo sapiens
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:379937] Castagnoli, L, 2008-11-06 12:55:54
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-170676
summation	[Summation:374946] Once activated, adenylate cyclase utilizes one molecule of A...

Referrals

(precedingEvent)	[Reaction:R-HSA-111962] PDE4A,C,D hydrolyse cAMP [Reaction:R-HSA-9644869] p-S54-PDE4B hydrolyses cAMP [Reaction:R-HSA-170685] Adenylaye cyclase increases the GTPase activity of G alpha-olf
(hasEvent)	[Pathway:R-HSA-170660] Adenylate cyclase activating pathway