Reactome | Adenylate cyclase converts ATP into cyclic AMP

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Adenylate cyclase converts ATP into cyclic AMP Show undefined attributes

catalystActivity	[CatalystActivity:10750024] adenylate cyclase activity of G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10750026
displayName	Adenylate cyclase converts ATP into cyclic AMP
eventOf	[Pathway:R-CEL-170660] Adenylate cyclase activating pathway - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-170685] Adenylaye cyclase increases the GTPase activity of G alpha-olf - Caenorhabditis elegans [Reaction:R-CEL-111962] PDE4A,C,D hydrolyse cAMP - Caenorhabditis elegans [Reaction:R-CEL-9644869] p-S54-PDE4B hydrolyses cAMP - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-170676] Adenylate cyclase converts ATP into cyclic AMP - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol]
isInDisease	false
isInferred	true
name	Adenylate cyclase converts ATP into cyclic AMP
output	[SimpleEntity:R-ALL-30389] cAMP [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent	[Reaction:R-CEL-170672] Galpha-olf:GTP binds to adenylate cyclase and activates it - Caenorhabditis elegans
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-170676
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-CEL-111962] PDE4A,C,D hydrolyse cAMP [Reaction:R-CEL-9644869] p-S54-PDE4B hydrolyses cAMP [Reaction:R-CEL-170685] Adenylaye cyclase increases the GTPase activity of G alpha-olf
(hasEvent)	[Pathway:R-CEL-170660] Adenylate cyclase activating pathway
(inferredTo)	[Reaction:R-HSA-170676] Adenylate cyclase converts ATP into cyclic AMP