Adenylate cyclase converts ATP into cyclic AMP

Stable Identifier
R-HSA-170676
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
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Adenylate cyclase converts ATP into cyclic AMP
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Once activated, adenylate cyclase utilizes one molecule of ATP to synthesize one molecule of cyclic AMP and pyrophosphate.
Literature References
PubMed ID Title Journal Year
8663304 Purification and characterization of a soluble form of mammalian adenylyl cyclase

Dessauer, CW, Gilman, AG

J Biol Chem 1996
Participants
Input
Output
Participates
as an event of
Catalyst Activity

adenylate cyclase activity of G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane]

Physical Entity
G alpha-olf:GTP:Adenylate cyclase (active) complex [plasma membrane] (Homo sapiens)
Activity
adenylate cyclase activity (GO:0004016)
Orthologous Events
Adenylate cyclase converts ATP into cyclic AMP (Bos taurus)
Adenylate cyclase converts ATP into cyclic AMP (Caenorhabditis elegans)
Adenylate cyclase converts ATP into cyclic AMP (Canis familiaris)
Adenylate cyclase converts ATP into cyclic AMP (Danio rerio)
Adenylate cyclase converts ATP into cyclic AMP (Dictyostelium discoideum)
Adenylate cyclase converts ATP into cyclic AMP (Drosophila melanogaster)
Adenylate cyclase converts ATP into cyclic AMP (Gallus gallus)
Adenylate cyclase converts ATP into cyclic AMP (Mus musculus)
Adenylate cyclase converts ATP into cyclic AMP (Rattus norvegicus)
Adenylate cyclase converts ATP into cyclic AMP (Sus scrofa)
Adenylate cyclase converts ATP into cyclic AMP (Xenopus tropicalis)
Cross References
Rhea
Authored
Jassal, B  (2004-03-31)
Le Novere, N  (2004-03-31)
Reviewed
Castagnoli, L  (2008-11-06)
Created
Jassal, B  (2006-01-10)
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