Reactome | p-S54-PDE4B hydrolyses cAMP

Schema > Reaction > Entries

p-S54-PDE4B hydrolyses cAMP Show undefined attributes

authored	[InstanceEdit:112007] Le Novere, N, Jassal, B, 2004-03-31 12:22:05
catalystActivity	[CatalystActivity:9644867] 3',5'-cyclic-AMP phosphodiesterase activity of p-S54-PDE4B-3 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9644866] Jassal, Bijay, 2019-04-26
crossReference	[DatabaseIdentifier:11880629] Rhea:25278
dbId	9644869
displayName	p-S54-PDE4B hydrolyses cAMP
edited	[InstanceEdit:379927] Jassal, Bijay, 2008-11-06
eventOf	[Pathway:R-HSA-180024] DARPP-32 events - Homo sapiens
input	[SimpleEntity:R-ALL-30389] cAMP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:375552] Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	p-S54-PDE4B hydrolyses cAMP cAMP hydrolysis by PDE4B
orthologousEvent	[Reaction:R-PFA-9644869] p-S54-PDE4B hydrolyses cAMP - Plasmodium falciparum [Reaction:R-DDI-9644869] p-S54-PDE4B hydrolyses cAMP - Dictyostelium discoideum [Reaction:R-CEL-9644869] p-S54-PDE4B hydrolyses cAMP - Caenorhabditis elegans [Reaction:R-DME-9644869] p-S54-PDE4B hydrolyses cAMP - Drosophila melanogaster [Reaction:R-GGA-9644869] p-S54-PDE4B hydrolyses cAMP - Gallus gallus [Reaction:R-XTR-9644869] p-S54-PDE4B hydrolyses cAMP - Xenopus tropicalis [Reaction:R-SSC-9644869] p-S54-PDE4B hydrolyses cAMP - Sus scrofa [Reaction:R-BTA-9644869] p-S54-PDE4B hydrolyses cAMP - Bos taurus [Reaction:R-CFA-9644869] p-S54-PDE4B hydrolyses cAMP - Canis familiaris [Reaction:R-RNO-9644869] p-S54-PDE4B hydrolyses cAMP - Rattus norvegicus [Reaction:R-MMU-9644869] p-S54-PDE4B hydrolyses cAMP - Mus musculus
output	[SimpleEntity:R-ALL-76577] AMP [cytosol]
precedingEvent	[Reaction:R-HSA-111930] Adenylate cyclase produces cAMP - Homo sapiens [Reaction:R-HSA-177284] PKA phosphorylates PDE4B - Homo sapiens [Reaction:R-HSA-170676] Adenylate cyclase converts ATP into cyclic AMP - Homo sapiens [Reaction:R-HSA-164377] Activated Adenylate cyclase catalyses cAMP synthesis - Homo sapiens
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:379937] Castagnoli, L, 2008-11-06 12:55:54
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9644869
summation	[Summation:9644868] cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B) hydr...

Referrals

(hasEvent)

[Pathway:R-HSA-180024] DARPP-32 events