Reactome | PDE4A,C,D hydrolyse cAMP

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PDE4A,C,D hydrolyse cAMP Show undefined attributes

authored	[InstanceEdit:112007] Le Novere, N, Jassal, B, 2004-03-31 12:22:05
catalystActivity	[CatalystActivity:111961] 3',5'-cyclic-AMP phosphodiesterase activity of PDE4A,C,D [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:111947] Schmidt, EE, 2004-03-26 09:35:25
crossReference	[DatabaseIdentifier:12667490] RHEA:25278
dbId	111962
displayName	PDE4A,C,D hydrolyse cAMP
edited	[InstanceEdit:379927] Jassal, Bijay, 2008-11-06
eventOf	[Pathway:R-HSA-180024] DARPP-32 events - Homo sapiens
input	[SimpleEntity:R-ALL-30389] cAMP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:375552] Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	PDE4A,C,D hydrolyse cAMP
orthologousEvent	[Reaction:R-CEL-111962] PDE4A,C,D hydrolyse cAMP - Caenorhabditis elegans [Reaction:R-DME-111962] PDE4A,C,D hydrolyse cAMP - Drosophila melanogaster [Reaction:R-GGA-111962] PDE4A,C,D hydrolyse cAMP - Gallus gallus [Reaction:R-XTR-111962] PDE4A,C,D hydrolyse cAMP - Xenopus tropicalis [Reaction:R-DRE-111962] PDE4A,C,D hydrolyse cAMP - Danio rerio [Reaction:R-SSC-111962] PDE4A,C,D hydrolyse cAMP - Sus scrofa [Reaction:R-BTA-111962] PDE4A,C,D hydrolyse cAMP - Bos taurus [Reaction:R-CFA-111962] PDE4A,C,D hydrolyse cAMP - Canis familiaris [Reaction:R-RNO-111962] PDE4A,C,D hydrolyse cAMP - Rattus norvegicus [Reaction:R-MMU-111962] PDE4A,C,D hydrolyse cAMP - Mus musculus
output	[SimpleEntity:R-ALL-76577] AMP [cytosol]
precedingEvent	[Reaction:R-HSA-111930] Adenylate cyclase produces cAMP - Homo sapiens [Reaction:R-HSA-170676] Adenylate cyclase converts ATP into cyclic AMP - Homo sapiens [Reaction:R-HSA-164377] Activated Adenylate cyclase catalyses cAMP synthesis - Homo sapiens
releaseDate	2008-12-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:379937] Castagnoli, L, 2008-11-06 12:55:54
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-111962
summation	[Summation:379964] cAMP-specific 3',5'-cyclic phosphodiesterases (PDE4A-D) hydr...
updateTrackers	[UpdateTracker:9791751] Update Tracker - [Reaction:111962] PDE4A,C,D hydrolyse cAMP - v26:[addLiteratureReference] [UpdateTracker:9791689] Update Tracker - [Reaction:111962] PDE4A,C,D hydrolyse cAMP - v27:[addSummation] [UpdateTracker:9777707] Update Tracker - [Reaction:111962] PDE4A,C,D hydrolyse cAMP - v69:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9791751] Update Tracker - [Reaction:111962] PDE4A,C,D hydrolyse cAMP - v26:[addLiteratureReference] [UpdateTracker:9791689] Update Tracker - [Reaction:111962] PDE4A,C,D hydrolyse cAMP - v27:[addSummation] [UpdateTracker:9777707] Update Tracker - [Reaction:111962] PDE4A,C,D hydrolyse cAMP - v69:[modifyText]
(hasEvent)	[Pathway:R-HSA-180024] DARPP-32 events

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