Reactome | TICAM1, RIP1-mediated IKK complex recruitment

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TICAM1, RIP1-mediated IKK complex recruitment Show undefined attributes

authored	[InstanceEdit:167907] Luo, F, 2005-11-10 11:23:18
created	[InstanceEdit:168919] de Bono, B, 2005-11-22 18:36:47
crossReference	[DatabaseIdentifier:12325418] BioModels Database:BIOMD0000000407 [DatabaseIdentifier:12325346] BioModels Database:BIOMD0000000883 [DatabaseIdentifier:12325404] BioModels Database:BIOMD0000000477
dbId	168927
displayName	TICAM1, RIP1-mediated IKK complex recruitment
edited	[InstanceEdit:450361] Shamovsky, V, 2009-12-16
eventOf	[Pathway:R-HSA-168164] Toll Like Receptor 3 (TLR3) Cascade - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:263660] MyD88-independent toll-like receptor signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-168930] Viral dsRNA:TLR3:TRIF complex recruits RIP1 - Homo sapiens [Reaction:R-HSA-9014342] K63-linked ubiquitination of RIP1 bound to the activated TLR complex - Homo sapiens [Reaction:R-HSA-9014343] IKBKG subunit of IKK complex binds K63pUb- RIP1 within the TLR3 complex - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:165954] RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B [LiteratureReference:433849] Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation
modified	[InstanceEdit:12325341] Wright, Adam, 2024-02-14
name	TICAM1, RIP1-mediated IKK complex recruitment
relatedSpecies	[Species:5229092] Hepatitis B virus [Species:5621375] Hepatitis C Virus [Species:5689680] Human herpesvirus 1 [Species:5617433] Rotavirus [Species:9031716] Influenza A virus
releaseDate	2010-12-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188961] Gay, NJ, 2006-04-24 16:48:17 [InstanceEdit:2582977] Fitzgerald, Katherine A, 2012-11-13
revised	[InstanceEdit:442879] Shamovsky, V, 2009-09-29
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-168927
summation	[Summation:177880] Receptor-interacting protein 1 (RIP1) mediates the activatio...

Referrals

(hasEvent)

[Pathway:R-HSA-168164] Toll Like Receptor 3 (TLR3) Cascade