Reactome | Addition of nucleotides leads to HIV-1 transcript elongation

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Addition of nucleotides leads to HIV-1 transcript elongation Show undefined attributes

authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:167180] Matthews, L, 2005-10-12 16:51:27
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	167181
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Addition of nucleotides leads to HIV-1 transcript elongation
edited	[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
eventOf	[Pathway:R-HSA-167246] Tat-mediated elongation of the HIV-1 transcript - Homo sapiens
figure	[Figure:113803] /figures/elong1.jpg
followingEvent	[Reaction:R-HSA-167192] Pol II elongation complex moves on the HIV-1 template as transcript elongates - Homo sapiens [Reaction:R-HSA-167090] 7-14 nt. Backtracking of Pol II complex on the HIV-1 template leading to elongation arrest - Homo sapiens [Reaction:R-HSA-167076] 2-4 nt.backtracking of Pol II complex on the HIV-1 template leading to elongation pausing - Homo sapiens
inferredFrom	[Reaction:R-HSA-112385] Addition of nucleotides leads to transcript elongation - Homo sapiens
input	[Complex:R-HSA-167185] HIV-1 elongation complex containing Tat [nucleoplasm] [SimpleEntity:R-ALL-9757634] NTP [nucleoplasm]
isInDisease	true
isInferred	true
literatureReference	[LiteratureReference:113806] Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. [LiteratureReference:113805] Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Addition of nucleotides leads to HIV-1 transcript elongation
output	[Complex:R-HSA-167184] HIV-1 Tat-containing processive elongation complex [nucleoplasm] [Complex:R-HSA-109634] TFIIH [nucleoplasm]
precedingEvent	[Reaction:R-HSA-167196] Recruitment of elongation factors to form HIV-1 elongation complex - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-167181
summation	[Summation:170761] This HIV-1 event was inferred from the corresponding human R...
updateTrackers	[UpdateTracker:9784214] Update Tracker - [Reaction:167181] Addition of nucleotides leads to HIV-1 transcript elongation - v54:[addLiteratureReference] [UpdateTracker:9775491] Update Tracker - [Reaction:167181] Addition of nucleotides leads to HIV-1 transcript elongation - v79:[add_removeInput]

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(updatedInstance)	[UpdateTracker:9784214] Update Tracker - [Reaction:167181] Addition of nucleotides leads to HIV-1 transcript elongation - v54:[addLiteratureReference] [UpdateTracker:9775491] Update Tracker - [Reaction:167181] Addition of nucleotides leads to HIV-1 transcript elongation - v79:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-167246] Tat-mediated elongation of the HIV-1 transcript
(precedingEvent)	[Reaction:R-HSA-167192] Pol II elongation complex moves on the HIV-1 template as transcript elongates [Reaction:R-HSA-167090] 7-14 nt. Backtracking of Pol II complex on the HIV-1 template leading to elongation arrest [Reaction:R-HSA-167076] 2-4 nt.backtracking of Pol II complex on the HIV-1 template leading to elongation pausing
(inferredTo)	[Reaction:R-HSA-112385] Addition of nucleotides leads to transcript elongation