Reactome | Addition of nucleotides 5 through 9 on the growing HIV-1 transcript

Schema > Reaction > Entries

Addition of nucleotides 5 through 9 on the growing HIV-1 transcript Show undefined attributes

authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
catalystActivity	[CatalystActivity:109910] DNA-directed 5'-3' RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:167126] Matthews, L, 2005-10-11 08:30:05
dbId	167136
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Addition of nucleotides 5 through 9 on the growing HIV-1 transcript
edited	[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
eventOf	[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape - Homo sapiens
followingEvent	[Reaction:R-HSA-167468] Abortive HIV-1 Initiation After Second Transition - Homo sapiens [Reaction:R-HSA-167117] Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition - Homo sapiens
inferredFrom	[Reaction:R-HSA-75873] Addition of Nucleotides 5 through 9 on the growing Transcript - Homo sapiens
input	[Complex:R-HSA-167124] HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] 5 × [SimpleEntity:R-ALL-9757634] NTP [nucleoplasm]
isInDisease	true
isInferred	true
literatureReference	[LiteratureReference:111276] A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes. [LiteratureReference:110389] Recycling of the general transcription factors during RNA polymerase II transcription. [LiteratureReference:111275] Strong natural pausing by RNA polymerase II within 10 bases of transcription start may result in repeated slippage and reextension of the nascent RNA. [LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation.
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Addition of nucleotides 5 through 9 on the growing HIV-1 transcript
output	[Complex:R-HSA-167100] HIV-1 transcription complex containing 9 nucleotide long transcript [nucleoplasm] 5 × [SimpleEntity:R-ALL-113541] PPi [nucleoplasm] [Complex:R-HSA-109629] TFIIA [nucleoplasm] [Complex:R-HSA-109626] TFIID [nucleoplasm] [Complex:R-HSA-109633] TFIIE [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-HSA-167113] Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-167136
summation	[Summation:111277] Formation of the second phosphodiester bond creates a 3-nt p...

Referrals

(precedingEvent)	[Reaction:R-HSA-167468] Abortive HIV-1 Initiation After Second Transition [Reaction:R-HSA-167117] Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition
(hasEvent)	[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape
(inferredTo)	[Reaction:R-HSA-75873] Addition of Nucleotides 5 through 9 on the growing Transcript