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Schema
>
Reaction
>
Entries
Addition of nucleotides 5 through 9 on the growing HIV-1 transcript
Show undefined attributes
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authored
[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
catalystActivity
[CatalystActivity:109910] DNA-directed RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
category
transition
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:167126] Matthews, L, 2005-10-11 08:30:05
crossReference
[DatabaseIdentifier:12020765] Mondo:0005109
dbId
167136
disease
[Disease:1660559] Human immunodeficiency virus infectious disease
displayName
Addition of nucleotides 5 through 9 on the growing HIV-1 transcript
edited
[InstanceEdit:165066] Matthews, L, 2005-07-26 23:29:22
eventOf
[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape - Homo sapiens
followingEvent
[Reaction:R-HSA-167468] Abortive HIV-1 Initiation After Second Transition - Homo sapiens
[Reaction:R-HSA-167117] Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition - Homo sapiens
inferredFrom
[Reaction:R-HSA-75873] Addition of Nucleotides 5 through 9 on the growing Transcript - Homo sapiens
input
[Complex:R-HSA-167124] HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm]
5 ×
[SimpleEntity:R-ALL-9757634] NTP [nucleoplasm]
isInDisease
true
isInferred
true
literatureReference
[LiteratureReference:111276] A role for TFIIH in controlling the activity of early RNA polymerase II elongation complexes.
[LiteratureReference:110389] Recycling of the general transcription factors during RNA polymerase II transcription.
[LiteratureReference:111275] Strong natural pausing by RNA polymerase II within 10 bases of transcription start may result in repeated slippage and reextension of the nascent RNA.
[LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation.
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name
Addition of nucleotides 5 through 9 on the growing HIV-1 transcript
output
[Complex:R-HSA-167100] HIV-1 transcription complex containing 9 nucleotide long transcript [nucleoplasm]
5 ×
[SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
[Complex:R-HSA-109629] TFIIA [nucleoplasm]
[Complex:R-HSA-109626] TFIID [nucleoplasm]
[Complex:R-HSA-109633] TFIIE [nucleoplasm]
precedingEvent
[BlackBoxEvent:R-HSA-167113] Addition of the fourth nucleotide on the nascent HIV-1 transcript: Second Transition - Homo sapiens
relatedSpecies
[Species:164493] Human immunodeficiency virus 1
releaseDate
2005-04-11
reviewStatus
[ReviewStatus:9821382] five stars
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-167136
summation
[Summation:111277] Formation of the second phosphodiester bond creates a 3-nt p...
updateTrackers
[UpdateTracker:9784335] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v54:[addLiteratureReference]
[UpdateTracker:9789537] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v37:[modifyText]
[UpdateTracker:9775442] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v79:[add_removeInput]
[UpdateTracker:9784568] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v53:[modifyText]
[UpdateTracker:9783008] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v57:[modifyText]
[UpdateTracker:9782566] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v59:[modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9784335] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v54:[addLiteratureReference]
[UpdateTracker:9789537] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v37:[modifyText]
[UpdateTracker:9775442] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v79:[add_removeInput]
[UpdateTracker:9784568] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v53:[modifyText]
[UpdateTracker:9783008] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v57:[modifyText]
[UpdateTracker:9782566] Update Tracker - [Reaction:167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - v59:[modifyText]
(precedingEvent)
[Reaction:R-HSA-167468] Abortive HIV-1 Initiation After Second Transition
[Reaction:R-HSA-167117] Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition
(hasEvent)
[Pathway:R-HSA-167162] RNA Polymerase II HIV Promoter Escape
(inferredTo)
[Reaction:R-HSA-75873] Addition of Nucleotides 5 through 9 on the growing Transcript
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