Reactome | TFIID [nucleoplasm]

Schema > Complex > Entries

TFIID [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:6805394] protein serine/threonine kinase activity of TFIID [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-167094] HIV-1 promoter:TFIID complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-109628] pol II promoter:TFIID complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-167124] HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] - Homo sapiens [Complex:R-HSA-167472] HIV-1 Promoter Escape Complex [nucleoplasm] - Homo sapiens [Complex:R-HSA-75859] Pol II Promoter Escape Complex [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-109636] Recognition and Binding of Core Promoter Elements by TFIID - Homo sapiens
created	[InstanceEdit:109625] Joshi-Tope, G, 2004-01-19 02:18:00
dbId	109626
displayName	TFIID [nucleoplasm]
hasComponent	[DefinedSet:R-HSA-5420880] TAF1,TAF1L [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-65551] TAF10 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-65553] TAF11 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-65555] TAF12 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-65557] TAF13 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9020680] TAF15 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-212408] TAF2 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-212446] TAF3 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-65541] TAF4 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-65559] TAF4B [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-65543] TAF5 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-65545] TAF6 [nucleoplasm] [CandidateSet:R-HSA-8866702] TAF7,TAF7L [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-212406] TAF8 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-212452] TAF9 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-212404] TAF9B [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-83718] TBP [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-109626] TFIID [nucleoplasm] - Mus musculus [Complex:R-RNO-109626] TFIID [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-109626] TFIID [nucleoplasm] - Canis familiaris [Complex:R-BTA-109626] TFIID [nucleoplasm] - Bos taurus [Complex:R-SSC-109626] TFIID [nucleoplasm] - Sus scrofa [Complex:R-DRE-109626] TFIID [nucleoplasm] - Danio rerio [Complex:R-XTR-109626] TFIID [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-109626] TFIID [nucleoplasm] - Gallus gallus [Complex:R-DME-109626] TFIID [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-109626] TFIID [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-109626] TFIID [nucleoplasm] - Dictyostelium discoideum [Complex:R-SPO-109626] TFIID [nucleoplasm] - Schizosaccharomyces pombe [Complex:R-SCE-109626] TFIID [nucleoplasm] - Saccharomyces cerevisiae
literatureReference	[LiteratureReference:5420856] Novel cofactors and TFIIA mediate functional core promoter selectivity by the human TAFII150-containing TFIID complex [LiteratureReference:5420864] The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger [LiteratureReference:5420866] Quantitative proteomics reveals regulation of dynamic components within TATA-binding protein (TBP) transcription complexes [LiteratureReference:5420868] TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9 [LiteratureReference:9020681] Cloning and characterization of human TAF20/15. Multiple interactions suggest a central role in TFIID complex formation [LiteratureReference:9020683] EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes [LiteratureReference:9967231] Structural insights into preinitiation complex assembly on core promoters
maxDepth	3
modified	[InstanceEdit:9967293] May, Bruce, 2025-09-27
name	TFIID
producedByEvent	[Reaction:R-HSA-167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript - Homo sapiens [Reaction:R-HSA-75873] Addition of Nucleotides 5 through 9 on the growing Transcript - Homo sapiens [Reaction:R-HSA-167474] Abortive HIV-1 Initiation Before Second Transition - Homo sapiens [Reaction:R-HSA-73946] Abortive initiation after formation of the first phosphodiester bond - Homo sapiens [Reaction:R-HSA-167477] Abortive HIV-1 initiation after formation of the first phosphodiester bond - Homo sapiens [Reaction:R-HSA-75856] Abortive Initiation Before Second Transition - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-109626
updateTrackers	[UpdateTracker:9898353] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v63:[addHasComponent, addLiteratureReference] [UpdateTracker:9866840] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v25:[add_removeHasComponent, updateContainedComponent] [UpdateTracker:9889455] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v49:[addLiteratureReference, add_removeHasComponent] [UpdateTracker:9894251] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v57:[addHasComponent] [UpdateTracker:9867729] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v26:[updateContainedComponent] [UpdateTracker:9972668] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v95:[removeHasComponent, removeLiteratureReference]

Referrals

(hasComponent)	[Complex:R-HSA-75859] Pol II Promoter Escape Complex [nucleoplasm] [Complex:R-HSA-167124] HIV-1 transcription complex containing 4 nucleotide long transcript [nucleoplasm] [Complex:R-HSA-167472] HIV-1 Promoter Escape Complex [nucleoplasm] [Complex:R-HSA-167094] HIV-1 promoter:TFIID complex [nucleoplasm] [Complex:R-HSA-167137] HIV-1 open pre-initiation complex [nucleoplasm] [Complex:R-HSA-167129] HIV-1 initiation complex [nucleoplasm] [Complex:R-HSA-167106] HIV-1 initiation complex with phosphodiester-PPi intermediate [nucleoplasm] [Complex:R-HSA-167101] HIV-1 transcription complex [nucleoplasm] [Complex:R-HSA-167119] HIV-1 transcription complex containing 3 nucleotide long transcript [nucleoplasm] [Complex:R-HSA-75881] pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] [Complex:R-HSA-75878] pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] [Complex:R-HSA-109878] pol II transcription complex [nucleoplasm] [Complex:R-HSA-83601] Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] [Complex:R-HSA-83551] Pol II initiation complex [nucleoplasm] [Complex:R-HSA-109876] pol II open pre-initiation complex [nucleoplasm] [Complex:R-HSA-109628] pol II promoter:TFIID complex [nucleoplasm]
(input)	[Reaction:R-HSA-109636] Recognition and Binding of Core Promoter Elements by TFIID
(output)	[Reaction:R-HSA-73946] Abortive initiation after formation of the first phosphodiester bond [Reaction:R-HSA-167477] Abortive HIV-1 initiation after formation of the first phosphodiester bond [Reaction:R-HSA-167136] Addition of nucleotides 5 through 9 on the growing HIV-1 transcript [Reaction:R-HSA-75856] Abortive Initiation Before Second Transition [Reaction:R-HSA-167474] Abortive HIV-1 Initiation Before Second Transition [Reaction:R-HSA-75873] Addition of Nucleotides 5 through 9 on the growing Transcript
(physicalEntity)	[CatalystActivity:6805394] protein serine/threonine kinase activity of TFIID [nucleoplasm]
(updatedInstance)	[UpdateTracker:9898353] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v63:[addHasComponent, addLiteratureReference] [UpdateTracker:9866840] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v25:[add_removeHasComponent, updateContainedComponent] [UpdateTracker:9889455] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v49:[addLiteratureReference, add_removeHasComponent] [UpdateTracker:9894251] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v57:[addHasComponent] [UpdateTracker:9867729] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v26:[updateContainedComponent] [UpdateTracker:9972668] Update Tracker - [Complex:109626] TFIID [nucleoplasm] - v95:[removeHasComponent, removeLiteratureReference]

© 2026 Reactome

Cite Us!