Reactome | Release of the HIV mRNA and Crm1 from Rev in the cytoplasm

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Release of the HIV mRNA and Crm1 from Rev in the cytoplasm Show undefined attributes

authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
category	dissociation
compartment	[Compartment:70101] cytosol [Compartment:13231] nuclear envelope
created	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	165028
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Release of the HIV mRNA and Crm1 from Rev in the cytoplasm
edited	[InstanceEdit:182779] Matthews, L, 2006-07-13 06:31:19
eventOf	[Pathway:R-HSA-165054] Rev-mediated nuclear export of HIV RNA - Homo sapiens
followingEvent	[Reaction:R-HSA-180709] Association of multimerized Rev with beta-importin - Homo sapiens [Reaction:R-HSA-165055] Hydrolysis of Ran:GTP to Ran:GDP - Homo sapiens
input	[Complex:R-HSA-180718] RanBP1:Ran-GTP:CRM1:Rev-bound mRNA complex [cytosol]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:6787485] The interaction of RNA helicase DDX3 with HIV-1 Rev-CRM1-RanGTP complex during the HIV replication cycle
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Release of the HIV mRNA and Crm1 from Rev in the cytoplasm
output	[EntityWithAccessionedSequence:R-HIV-187209] HIV-1 unspliced RNA [cytosol] [Complex:R-HSA-180686] RAN:GTP [cytosol] [EntityWithAccessionedSequence:R-HSA-167651] RANBP1 [nuclear envelope] [EntityWithAccessionedSequence:R-HIV-173267] REV (P04618) protein [cytosol] [Polymer:R-HIV-165543] Rev-multimer [cytosol] [EntityWithAccessionedSequence:R-HSA-165539] XPO1 [cytosol]
precedingEvent	[Reaction:R-HSA-180739] Association of RanBP1 with Ran-GTP:CRM1:Rev:mRNA complex - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:192365] Kumar, A, 2007-01-31 22:47:49
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-165028
summation	[Summation:179145] The association of RanBp1 with RanGTP:CRM1:Rev promotes dis...
updateTrackers	[UpdateTracker:9784531] Update Tracker - [Reaction:165028] Release of the HIV mRNA and Crm1 from Rev in the cytoplasm - v54:[addLiteratureReference, modifyText] [UpdateTracker:9787681] Update Tracker - [Reaction:165028] Release of the HIV mRNA and Crm1 from Rev in the cytoplasm - v44:[add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9784531] Update Tracker - [Reaction:165028] Release of the HIV mRNA and Crm1 from Rev in the cytoplasm - v54:[addLiteratureReference, modifyText] [UpdateTracker:9787681] Update Tracker - [Reaction:165028] Release of the HIV mRNA and Crm1 from Rev in the cytoplasm - v44:[add_removeOutput]
(precedingEvent)	[Reaction:R-HSA-165055] Hydrolysis of Ran:GTP to Ran:GDP [Reaction:R-HSA-180709] Association of multimerized Rev with beta-importin
(hasEvent)	[Pathway:R-HSA-165054] Rev-mediated nuclear export of HIV RNA