Reactome | REV (P04618) protein [cytosol]

Schema > EntityWithAccessionedSequence > Entries

REV (P04618) protein [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HIV-165551] Rev-bound HIV-1 mRNA [cytosol] - Human immunodeficiency virus 1 [Complex:R-HSA-3149451] Assembling HIV virion [plasma membrane] - Homo sapiens [Complex:R-HSA-173801] RTC with tRNA primer:RNA template [cytosol] - Homo sapiens [Complex:R-HSA-173814] RTC (Reverse Transcription Complex) with RNA template [cytosol] - Homo sapiens [Complex:R-HSA-173789] RTC with extensive RNase-H digestion [cytosol] - Homo sapiens [Complex:R-HSA-173653] uncoated viral complex [cytosol] - Homo sapiens [Complex:R-HSA-188943] Encapsidated viral core [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-3149454] Packaging of HIV virion on the host cell plasma membrane - Homo sapiens
created	[InstanceEdit:173199] Gopinathrao, G, 2006-02-08 16:38:07
dbId	173267
deleted	[Deleted:3006577] Deletion of instances: 175501, 174992, 173122
displayName	REV (P04618) protein [cytosol]
endCoordinate	-1
goCellularComponent	[Compartment:436407] host cell cytosol
inDisease	false
maxDepth	1
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	REV (P04618) protein
producedByEvent	[Reaction:R-HSA-165028] Release of the HIV mRNA and Crm1 from Rev in the cytoplasm - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P04618] UniProt:P04618 rev
referenceType	ReferenceGeneProduct
repeatedUnitOf	[Polymer:R-HIV-165543] Rev-multimer [cytosol] - Human immunodeficiency virus 1
schemaClass	EntityWithAccessionedSequence
species	[Species:164493] Human immunodeficiency virus 1
stId	R-HIV-173267
startCoordinate	1

Referrals

(replacementInstances)	[Deleted:3006577] Deletion of instances: 175501, 174992, 173122
(hasComponent)	[Complex:R-HSA-3149451] Assembling HIV virion [plasma membrane] [Complex:R-HSA-188943] Encapsidated viral core [cytosol] [Complex:R-HSA-173653] uncoated viral complex [cytosol] [Complex:R-HSA-173814] RTC (Reverse Transcription Complex) with RNA template [cytosol] [Complex:R-HSA-173801] RTC with tRNA primer:RNA template [cytosol] [Complex:R-HSA-182804] RTC with nicked minus sssDNA:tRNA primer:RNA template [cytosol] [Complex:R-HSA-173773] RTC with degraded RNA template and minus sssDNA [cytosol] [Complex:R-HSA-173779] RTC with minus sssDNA transferred to 3'-end of viral RNA template [cytosol] [Complex:R-HSA-173786] RTC with minus strand DNA synthesis initiated from 3'-end [cytosol] [Complex:R-HSA-173789] RTC with extensive RNase-H digestion [cytosol] [Complex:R-HSA-173764] RTC with extending minus strand DNA [cytosol] [Complex:R-HSA-182880] RTC with extending second-strand DNA [cytosol] [Complex:R-HSA-173824] RTC without viral RNA template [cytosol] [Complex:R-HSA-173792] RTC with annealed complementary PBS seqments in +sssDNA and -strand DNA [cytosol] [Complex:R-HSA-188560] RTC with duplex DNA containing discontinuous plus strand flap [cytosol] [Complex:R-HSA-177532] viral DNA bound with Integrase in PIC [cytosol] [Complex:R-HSA-175143] PIC (PreIntegration Complex) [cytosol] [Complex:R-HSA-173664] Viral core surrounded by Matrix layer [cytosol] [Complex:R-HIV-165551] Rev-bound HIV-1 mRNA [cytosol] [Complex:R-HSA-180731] RTC with minus sssDNA containing deaminated C residues:tRNA primer:RNA template [cytosol] [Complex:R-HSA-173774] RTC with minus sssDNA:tRNA primer:RNA template [cytosol] [Complex:R-HSA-177526] IN bound to sticky 3' ends of viral DNA in PIC [cytosol]
(input)	[Reaction:R-HSA-3149454] Packaging of HIV virion on the host cell plasma membrane
(output)	[Reaction:R-HSA-165028] Release of the HIV mRNA and Crm1 from Rev in the cytoplasm
(repeatedUnit)	[Polymer:R-HIV-165543] Rev-multimer [cytosol]

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