Reactome | Suicidal integration leading to inverted circle formation

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Suicidal integration leading to inverted circle formation Show undefined attributes

authored	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:164848] Gopinathrao, G, 2005-06-29 16:40:43
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	164845
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Suicidal integration leading to inverted circle formation
edited	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
eventOf	[Pathway:R-HSA-177539] Autointegration results in viral DNA circles - Homo sapiens
input	[Complex:R-HSA-175416] IN bound to sticky 3' ends of viral DNA in PIC [nucleoplasm]
isInDisease	true
isInferred	false
literatureReference	[Book:175927] 9780879695712 Integration Retroviruses Coffin, JM [LiteratureReference:175622] HIV cDNA integration: molecular biology and inhibitor development [Book:175907] 9781461559252 Retroviral cDNA integration: mechanism, applications and inhibition Genetic Engineering: Principles and Methods Setlow, Jane K
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Suicidal integration leading to inverted circle formation
output	[Complex:R-HIV-175415] Autointegrated viral DNA as an inverted circle [nucleoplasm] 2 × [EntityWithAccessionedSequence:R-HIV-175288] IN (Integrase) (P04585) protein [nucleoplasm] [Complex:R-HSA-177527] viral PIC proteins [nucleoplasm]
precedingEvent	[Reaction:R-HSA-162590] Import of PIC to the Host Nucleus - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188934] Bushman, FD, 2006-10-30 22:19:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-164845
summation	[Summation:180156] Following the integrase-mediated strand transfer reaction of...
updateTrackers	[UpdateTracker:9787522] Update Tracker - [Reaction:164845] Suicidal integration leading to inverted circle formation - v44:[add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9787522] Update Tracker - [Reaction:164845] Suicidal integration leading to inverted circle formation - v44:[add_removeOutput]
(hasEvent)	[Pathway:R-HSA-177539] Autointegration results in viral DNA circles

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