Suicidal integration leading to inverted circle formation

Stable Identifier
R-HSA-164845
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
nucleoplasm
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Suicidal integration leading to inverted circle formation
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Following the integrase-mediated strand transfer reaction of autointegration, the integration complex must be disassembled and the gapped intermediate repaired, just as in normal integration.

Literature References
PubMed ID Title Journal Year
8883604 HIV cDNA integration: molecular biology and inhibitor development

Farnet, CM, Bushman, FD

AIDS 1996
  Retroviruses

Coffin, JM, Hughes, SH, Varmus, HE

  1997
  Genetic Engineering: Principles and Methods

Setlow, JK

  1998
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Gopinathrao, G  (2006-05-19)
D'Eustachio, P  (2006-05-19)
Reviewed
Bushman, FD  (2006-10-31)
Created
Gopinathrao, G  (2005-06-29)
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