Reactome | First strand transfer mediated by Repeated (R) sequence

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First strand transfer mediated by Repeated (R) sequence Show undefined attributes

authored	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:164501] D'Eustachio, P, 2005-05-24 15:07:45
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	164503
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	First strand transfer mediated by Repeated (R) sequence
edited	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
eventOf	[Pathway:R-HSA-164516] Minus-strand DNA synthesis - Homo sapiens
figure	[Figure:180419] /figures/RT_event3.jpg
followingEvent	[Reaction:R-HSA-164520] Minus strand DNA synthesis resumes - Homo sapiens
input	[Complex:R-HSA-173773] RTC with degraded RNA template and minus sssDNA [cytosol]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:182828] Premature strand transfer by the HIV-1 reverse transcriptase during strong-stop DNA synthesis [LiteratureReference:182841] Sequences in the 5' and 3' R elements of human immunodeficiency virus type 1 critical for efficient reverse transcription
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	First strand transfer mediated by Repeated (R) sequence
output	[Complex:R-HSA-173779] RTC with minus sssDNA transferred to 3'-end of viral RNA template [cytosol]
precedingEvent	[Reaction:R-HSA-182859] RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2006-11-14
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188936] Hughes, SH, 2006-10-30 22:00:51
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-164503
summation	[Summation:177432] The minus strand strong stop DNA (-sssDNA) is transferred to...

Referrals

(hasEvent)	[Pathway:R-HSA-164516] Minus-strand DNA synthesis
(precedingEvent)	[Reaction:R-HSA-164520] Minus strand DNA synthesis resumes

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