Reactome | Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation

Schema > Pathway > Entries

Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation Show undefined attributes

authored	[InstanceEdit:163839] D'Eustachio, P, 2005-05-07 21:32:05
created	[InstanceEdit:163839] D'Eustachio, P, 2005-05-07 21:32:05
dbId	163841
diseasePathways	[Pathway:R-HSA-9674519] Defective F8 sulfation at Y1699 - Homo sapiens [Pathway:R-HSA-9673240] Defective gamma-carboxylation of F9 - Homo sapiens
displayName	Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
edited	[InstanceEdit:165080] D'Eustachio, P, 0000-00-00 00:00:00
eventOf	[Pathway:R-HSA-597592] Post-translational protein modification - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:258214] post-translational protein modification
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-HSA-159854] Gamma-carboxylation, transport, and amino-terminal cleavage of proteins - Homo sapiens [Pathway:R-HSA-204626] Hypusine synthesis from eIF5A-lysine - Homo sapiens [Pathway:R-HSA-5358493] Synthesis of diphthamide-EEF2 - Homo sapiens [Pathway:R-HSA-1663150] The activation of arylsulfatases - Homo sapiens [Reaction:R-HSA-6788650] ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins - Homo sapiens [Reaction:R-HSA-6788867] FN3K phosphorylates ketosamines - Homo sapiens [Reaction:R-HSA-6788855] FN3KRP phosphorylates PsiAm, RibAm - Homo sapiens [Reaction:R-HSA-9668023] TPST1,2 transfer SO4(2-) from PAPS to FVIII - Homo sapiens [Pathway:R-HSA-9629569] Protein hydroxylation - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2023-09-13
maxDepth	4
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
orthologousEvent	[Pathway:R-MMU-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Mus musculus [Pathway:R-RNO-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Rattus norvegicus [Pathway:R-CFA-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Canis familiaris [Pathway:R-BTA-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Bos taurus [Pathway:R-SSC-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Sus scrofa [Pathway:R-DRE-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Danio rerio [Pathway:R-XTR-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Xenopus tropicalis [Pathway:R-GGA-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Gallus gallus [Pathway:R-DME-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Drosophila melanogaster [Pathway:R-DDI-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Dictyostelium discoideum [Pathway:R-CEL-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Caenorhabditis elegans [Pathway:R-SPO-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Schizosaccharomyces pombe [Pathway:R-SCE-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Saccharomyces cerevisiae [Pathway:R-PFA-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Plasmodium falciparum
releaseDate	2005-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:165118] Orlean, P, Stafford, DW, 0000-00-00 00:00:00
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-163841
summation	[Summation:597590] After translation, many newly formed proteins undergo furthe...
updateTrackers	[UpdateTracker:9792097] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v24:[addHasEvent, updateContainedPathway] [UpdateTracker:9785600] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v51:[addHasEvent, modifyText] [UpdateTracker:9792479] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v20:[updateContainedPathway] [UpdateTracker:9779040] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v66:[updateContainedPathway] [UpdateTracker:9782343] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v59:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9842345] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - v86:[addHasEvent, modifyText, updateIndirectRLE] [UpdateTracker:9864359] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - v88:[updateIndirectRLE] [UpdateTracker:9791876] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v25:[updateIndirectRLE] [UpdateTracker:9776950] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v73:[addHasEvent] [UpdateTracker:9788558] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v41:[addHasEvent] [UpdateTracker:9777806] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v69:[updateIndirectRLE] [UpdateTracker:9783946] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v55:[addHasEvent, updateContainedPathway] [UpdateTracker:9788022] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v44:[updateIndirectRLE] [UpdateTracker:9853198] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - v87:[updateIndirectRLE] [UpdateTracker:9790699] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v33:[add_removeSummation, removeHasEvent, updateContainedPathway, updateIndirectRLE]

Referrals

(hasEvent)	[Pathway:R-HSA-597592] Post-translational protein modification
(hasEncapsulatedEvent)	[Pathway:R-HSA-6806664] Metabolism of vitamin K
(normalPathway)	[Pathway:R-HSA-9674519] Defective F8 sulfation at Y1699 [Pathway:R-HSA-9673240] Defective gamma-carboxylation of F9
(updatedInstance)	[UpdateTracker:9792097] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v24:[addHasEvent, updateContainedPathway] [UpdateTracker:9785600] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v51:[addHasEvent, modifyText] [UpdateTracker:9792479] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v20:[updateContainedPathway] [UpdateTracker:9779040] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v66:[updateContainedPathway] [UpdateTracker:9782343] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v59:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9842345] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - v86:[addHasEvent, modifyText, updateIndirectRLE] [UpdateTracker:9864359] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - v88:[updateIndirectRLE] [UpdateTracker:9791876] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v25:[updateIndirectRLE] [UpdateTracker:9776950] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v73:[addHasEvent] [UpdateTracker:9788558] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v41:[addHasEvent] [UpdateTracker:9777806] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v69:[updateIndirectRLE] [UpdateTracker:9783946] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v55:[addHasEvent, updateContainedPathway] [UpdateTracker:9788022] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v44:[updateIndirectRLE] [UpdateTracker:9853198] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - v87:[updateIndirectRLE] [UpdateTracker:9790699] Update Tracker - [Pathway:163841] Gamma carboxylation, hypusine formation and arylsulfatase activation - v33:[add_removeSummation, removeHasEvent, updateContainedPathway, updateIndirectRLE]

Cite Us!