Reactome | Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation

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Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation Show undefined attributes

created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10911704
displayName	Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
eventOf	[Pathway:R-DME-597592] Post-translational protein modification - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:258214] post-translational protein modification
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DME-204626] Hypusine synthesis from eIF5A-lysine - Drosophila melanogaster [Pathway:R-DME-5358493] Synthesis of diphthamide-EEF2 - Drosophila melanogaster [Pathway:R-DME-1663150] The activation of arylsulfatases - Drosophila melanogaster [Reaction:R-DME-6788650] ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins - Drosophila melanogaster [Pathway:R-DME-9629569] Protein hydroxylation - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-163841
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-597592] Post-translational protein modification
(hasEncapsulatedEvent)	[Pathway:R-DME-6806664] Metabolism of vitamin K
(inferredTo)	[Pathway:R-HSA-163841] Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation

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