Reactome | F8(392-759) [extracellular region]

Schema > EntityWithAccessionedSequence > Entries

F8(392-759) [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-HSA-9670192] FVIIIa variants [extracellular region] - Homo sapiens
created	[InstanceEdit:158298] D'Eustachio, P, 2005-01-20 14:44:36
dbId	158199
displayName	F8(392-759) [extracellular region]
endCoordinate	759
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-158199] F8 [extracellular region] - Mus musculus [EntityWithAccessionedSequence:R-RNO-158199] F8 [extracellular region] - Rattus norvegicus [EntityWithAccessionedSequence:R-BTA-158199] F8 [extracellular region] - Bos taurus
maxDepth	1
modified	[InstanceEdit:9967162] D'Eustachio, Peter, 2025-09-26
name	F8(392-759) FVIII (392-759) factor VIIIa A2 polypeptide
producedByEvent	[Reaction:R-HSA-9670049] Defects in F8 A1 domain accelerate dissociation of the A2 domain - Homo sapiens [Reaction:R-HSA-9670014] Factor VIIIa dissociates - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P00451] UniProt:P00451 F8
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-158199
startCoordinate	392
updateTrackers	[UpdateTracker:9880884] Update Tracker - [EntityWithAccessionedSequence:158199] factor VIIIa A2 polypeptide [extracellular region] - v45:[addName] [UpdateTracker:9901023] Update Tracker - [EntityWithAccessionedSequence:158199] factor VIIIa A2 polypeptide [extracellular region] - v72:[modifyEndCoordinate, modifyName, modifyStartCoordinate] [UpdateTracker:9939881] Update Tracker - [EntityWithAccessionedSequence:158199] FVIII (392-759) [extracellular region] - v92:[removeName]

Referrals

(updatedInstance)	[UpdateTracker:9880884] Update Tracker - [EntityWithAccessionedSequence:158199] factor VIIIa A2 polypeptide [extracellular region] - v45:[addName] [UpdateTracker:9901023] Update Tracker - [EntityWithAccessionedSequence:158199] factor VIIIa A2 polypeptide [extracellular region] - v72:[modifyEndCoordinate, modifyName, modifyStartCoordinate] [UpdateTracker:9939881] Update Tracker - [EntityWithAccessionedSequence:158199] FVIII (392-759) [extracellular region] - v92:[removeName]
(hasComponent)	[Complex:R-HSA-9670192] FVIIIa variants [extracellular region] [Complex:R-HSA-9670038] factor VIIIa with defective A1 domain [extracellular region] [Complex:R-HSA-158307] factor VIIIa [extracellular region]
(output)	[Reaction:R-HSA-9670049] Defects in F8 A1 domain accelerate dissociation of the A2 domain [Reaction:R-HSA-9670014] Factor VIIIa dissociates

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